Review
Open access
Sep 2026
This review critically summarizes recent advances in herbal nanoformulations, emphasizing disease-specific molecular targets, BBB-targeting strategies, comparative nanocarrier systems, pharmacokinetic optimization, intracellular trafficking, and translational challenges.
D. Mittal, Pavitra Solanki, G. K. Jain et al.
· 3 Biotech · 1 citation
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Review
Oct 2026
Parkinson's disease (PD) is a progressive neurodegenerative disorder driven by oxidative imbalance, mitochondrial dysfunction, and persistent neuroinflammation, yet current pharmacological interventions provide symptomatic relief but fail to halt neuronal degeneration largely owing to complex pathological mechanisms an...
Qu-Cheng Huang, Yun-Wei Sun, Yue Duan et al.
· International Journal of Bio... · 0 citations
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Review
Sep 2026
The current knowledge on polyherbal synergy, nanocarrier-based targeting methods, and nose-to-brain delivery strategies to treat neurodegenerative disorders are summarized, highlighting their potential therapeutic applications, underlying mechanisms, translational issues, regulatory factors, and emerging trends such as...
Mahalakshmi Seelam, Varalakshmi Sagili
· Drug Delivery Letters · 0 citations
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Review
Open access
Sep 2026
This review discusses multi-target neuroprotective mechanisms of curcumin, critically reviews the preclinical success and human clinical trial outcomes, and highlights advanced nano formulations (solid lipid nanoparticles, colloidal sub-micron dispersions, polymeric nanoparticles, multi-walled carbon nanotubes and exos...
V. S, Sarupruthiya M, Jeevitha D et al.
· International Journal Of Rec... · 0 citations
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Review
Open access
Sep 2026
Background and Objectives: The main neurodegenerative diseases (NDs)—Alzheimer’s disease (AD), Parkinson’s disease (PD), multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS)—represent a growing global health burden with no available disease-modifying therapies. Curcumin, a polyphenol from Curcuma longa, is...
Alejandra Castelló-Guillen, Marta Garrido-Reig, Jordi Caplliure-Llopis et al.
· Pharmaceuticals · 0 citations
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Review
Sep 2026
Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by the selective loss of dopaminergic neurons in the substantia nigra, which gives rise to characteristic motor and non-motor behavioral impairments. Disease-modifying therapies remain elusive, largely due to the restrictive nature of the blood...
Qu-Cheng Huang, Yuan-Yuan Zuo, Yi-Ning Xie et al.
· ACS Biomaterials Science & E... · 0 citations
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