Sep 2026· Naunyn-Schmiedeberg's Archives of Pharmacology· 0 citations· 57 references
Medicine
TL;DR
Study results indicate that rufigallol may protect against cisplatin-induced nephrotoxicity; however, additional research is needed to confirm its effectiveness in humans.
ABSTRACT Cisplatin is a widely used chemotherapeutic agent; however, its clinical utility is frequently limited by dose‐dependent adverse effects, particularly hepatotoxicity and nephrotoxicity. Luteolin, a naturally occurring flavonoid abundant in various medicinal plants, exhibits well‐documented antioxidant and anti...
Ö. Temiz, Suna Kızılyıldırım, Tuba Ozdemir-Sanci et al.· Journal of biochemical and m...· 0 citations
Background: Cisplatin is an effective and commonly used anticancer drug, but its therapeutic application is constrained by its potential to cause kidney injury. This experimental study investigated nebivolol protective effects, which is a third-generation selective β1-adrenoceptor blocker with additional β3-adrenocepto...
Jamal J. Omer, D. Ibrahim, Mogahed A. Al-Shawia et al.· University of Science and Te...· 0 citations
Cisplatin (CIS) is an effective cancer therapy, but its nephrotoxicity often causes acute kidney injury, hence restricting its usage. This study assessed the nephroprotective effects of Pinctada radiata lipid extract (PRE) against cisplatin-induced kidney injury. Lipids from Pinctada radiata were extracted using chloro...
Nada S. Badr, Heba Abdelhamid Abdelkafar Shreif, Eman Radwan et al.· Journal of Basic and Applied...· 0 citations
Cisplatin, which can be very effective as a chemotherapeutic agent, is considerably limited in its clinical application by its known tendencies towards nephrotoxicity, a problem that is mainly due to oxidative stress, inflammation and tubular damage. To appraise the ameliorative and antioxidant action of Moringa oleife...
Hiba Abdulkreem· Kerbala Journal of Veterinar...· 0 citations
Objective: Cisplatin is a well-known anticancer drug whose use has been limited due to a variety of side effects. Evidence has confirmed that cisplatin consumption is associated with cardiac toxicity. Unfortunately, no drug has yet been found to treat cardiac toxicity or reduce the side effects caused by cisplatin. How...
Hoori Heidari Kahkesh, Negin Amini, Mohammad Badavi et al.· Avicenna Journal of Phytomed...· 0 citations