Amphora Coffeaeformis Extract as a Novel Therapeutic Agent against Gamma Radiation-Induced Infertility in Male Rats.

Ganoderic acid D as a potential modulator of steroidogenic enzymes: Protective effects of Cucurbita maxima Duch. seed extract against nonylphenol-induced reproductive toxicity

Methanolic extract of Lippia graveolens (Mexican oregano) protects against iron- and lead-induced genomic damage without evidence of toxicity in CD-1 mice.

ETHNOPHARMACOLOGICAL RELEVANCE Lippia graveolens Kunth (Mexican oregano) is traditionally used to treat gastrointestinal, respiratory, and inflammatory conditions. Its phenolic constituents provide a rationale for investigating additional biological properties, including protection against chemically induced genetic da...

Pulicaria odora as a Natural Antioxidant Remedy for Metribuzin-induced Toxicity

Co-administration of P. odora extract significantly reversed metribuzin-induced toxicity in Wistar rats, restoring biomarkers and alleviating hepatic and renal toxicity by reducing transaminases, urea, creatinine, cholesterol and triglycerides and its antioxidant properties were highlighted.

Hormetic Antioxidant Effects of Uncaria gambir on Male Reproductive Function: A Comprehensive Experimental and Computational Analysis

Oxidative stress is a key mechanism underlying nicotine-induced male reproductive dysfunction, yet evidence-based phytopharmacological interventions remain limited. Uncaria gambir Roxb., a catechin-rich medicinal plant from West Sumatra, Indonesia, exhibits strong antioxidant potential; however, a comprehensive multi-r...

Protective effects of Astragalus microcephalus polysaccharides combined with vitamin E and selenium against mercury-induced ovarian toxicity in female rats.

The results suggest that Astragalus microcephalus polysaccharides, particularly in synergy with vitamin E and selenium, offers a potential therapeutic strategy for managing heavy metal-induced reproductive damage.

Evaluation of the Protective and Immunomodulatory Efficacy of Annona Muricata Leaf Extract Against Allura Red (E129)-Induced Nephrotoxicity and Inflammation in Male Albino Rats

Background: Synthetic food colorants, including Allura Red (E129), are extensively utilized in ultra-processed foods and have been implicated in inducing oxidative stress, cellular damage, and inflammatory responses. Objective: This study aimed to evaluate the protective and immunomodulatory efficacy of an aqueous extr...