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A New aspect of the pathology of brain tuberculosis: Mycobacterium tuberculosis infects and alters human neural progenitor cells

Thanthrige Thiunuwan Priyathilaka Melinda Herbath Mohan Kumar C. Laaker Michael P. Schwartz Connie S. Lebakken Z. Fabry Matyas Sandor
Aug 2026 · bioRxiv · 0 citations · 89 references
Biology

TL;DR

Findings indicate that brain organoids and NPC-based in vitro platforms provide a novel approach for studying brain tuberculosis, and that decreased NPC function may contribute to brain tuberculosis-induced cognitive disease.

DOI Semantic Scholar
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