Sep 2026· Journal of Theoretical Biology· pp.
112600
· 0 citations· 31 references
Medicine
Abstract
We incorporate stochastic fluctuations into an epidemic-behavior coevolution model and study its threshold dynamics and stationary distributions. By introducing the stochastic basic reproduction number R0σ, the behavioral threshold d, and two potential infection proportions RPσ,1 and RPσ,2, we establish conditions for disease extinction and persistence. For persistent dynamics, we derive explicit stationary densities and associated mean infection levels on the two behavioral boundaries. When the dynamics do not converge to either boundary, we establish a unique ergodic stationary distribution and derive a local bivariate log-normal approximation near the quasi-equilibrium. Comparison with the deterministic counterpart reveals that stochastic perturbations reduce the basic reproduction number as well as the two potential infection proportions, indicating that stochasticity may induce disease extinction, while widespread adoption of self-protective behaviors is required only when disease transmission is strong. Numerical simulations are performed to illustrate the theoretical results, and model fitting to COVID-19 data further demonstrates the relevance of the proposed framework to real epidemic scenarios.
The derivation of the rigorous sufficient conditions that characterize both the extinction and the long-term persistence of disease dynamics are derived, including a threshold parameter Λ, expressed in terms of the switching exponents ρξ(t) and ζξ(t), from a nonlinear stochastic SIRS epidemic model evolving in a random...
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Much of the literature and intuition associated with mathematical epidemiology is driven by deterministic models, which are a reasonable assumption when the population size is large. Stochastic models, especially individual based models, are however considered vital when dealing with small population sizes, especially...
Daniel R. Higgins, M. Keeling, Louise Dyson· bioRxiv· 0 citations
In this paper, we study a stochastic Susceptible-Infected-Removed (SIR) model where the infection and the recovery rates depend on individual covariates for susceptibility and infectiousness of the infector and the infectee. Such models allow explicit nonlinearity in the incidence term. They are also important from a p...
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