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A boundary-semantic synergy learning network for breast ultrasound lesion segmentation

Aug 2026 · Scientific Reports · 0 citations

Abstract

Breast ultrasound (BUS) image segmentation remains challenging due to speckle noise, blurred lesion boundaries, and substantial variations in lesion scale. To address these issues, we propose a Dual-branch Semantic-Aware Segmentation Network (D-SAS) that enhances lesion representation through boundary enhancement, multi-scale semantic perception, and boundary-semantic collaborative fusion. Specifically, a Speckle Suppression Boundary Gate (SSBG) is designed to suppress noise interference and strengthen boundary representation. An Adaptive Atrous Selector (AAS) is introduced to dynamically aggregate multi-scale contextual information via pixel-wise adaptive weighting. In addition, a Synergistic Fusion Head (SFH) facilitates effective interaction between boundary and semantic features through bidirectional attention guidance and uncertainty-aware fusion. Experimental results demonstrate the effectiveness of the proposed method. D-SAS achieves Dice scores of 82.10% and 89.14% and IoU values of 70.21% and 81.34% on the BUSI and BUSI_WHU datasets, respectively, outperforming existing state-of-the-art methods. Furthermore, under the cross-dataset setting of BUSI_WHU-to-UDIAT, D-SAS achieves a Dice score of 80.95% and an IoU of 72.82%, demonstrating strong robustness to domain shifts caused by different imaging devices and clinical centers. These results indicate that D-SAS provides accurate breast lesion segmentation with promising cross-dataset generalization capability.

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