Aug 2026· Clinical Psychology and Psychotherapy· Vol 33 5, pp.
e70329
· 0 citations· 55 references
Medicine
Abstract
Dimensional models of psychopathology offer an alternative to traditional categorical systems, yet research examining the incremental validity of transdiagnostic dimensions over diagnostic categories remains limited. The current study uses data from 685 outpatients, who presented at an academic medical centre for psychological assessment, to determine whether transdiagnostic dimensions derived from commonly used clinical assessment measures (Fear/Distress, Narcissistic Antagonism, Attachment, Flexible Thinking, Somatization, External Coping and Anger/Aggression) increment the variance in suicidal ideation, cognitive functioning, psychosocial functioning, pain and quality of life explained by diagnostic categories. When considered in isolation, diagnostic categories significantly predicted pain (R2 = 0.08) but did not predict the other four outcome measures. When transdiagnostic dimensions were added to the model, all five outcome models were significant, and dimensions explained substantial additional variance: suicidal ideation (ΔR2 = 0.41), cognitive concerns (ΔR2 = 0.28), psychosocial functioning (ΔR2 = 0.55), pain (ΔR2 = 0.21) and quality of life (ΔR2 = 0.38). Across models, somatization emerged as the most robust predictor and was significantly associated with cognitive concerns, psychosocial functioning, pain and quality of life. When the order of entry was reversed, a trauma diagnosis significantly incremented transdiagnostic dimensions when predicting suicidal ideation. Overall, these results suggest that transdiagnostic dimensions demonstrate substantial incremental validity over categorical diagnoses in predicting clinically meaningful outcomes. These findings support dimensional approaches to psychopathology and suggest that existing clinical data can be leveraged to implement dimensional conceptualizations in practice.
PURPOSE
The transdiagnostic approach provides an efficacious and efficient alternative to disorder-based psychological therapies. Emerging evidence suggests that a single main process may maintain psychological distress, but its identity is unclear, and some studies have found additional processes. We included a larger...
Warren Mansell, Isabeau K. Tindall, Alex R. Wheeler et al.· Journal of Affective Disorde...· 0 citations
The Hierarchical Taxonomy of Psychopathology (HiTOP) has gained substantial empirical support as a dimensional model for understanding severe psychopathology. However, the integration of the Level of Personality Functioning (LPF) into this framework remains debated, and its specific contribution to understanding psycho...
Marco Lauriola, Costanza Falzetti, F. Noto et al.· Psychiatry International· 0 citations
Background Perceived stress is a central transdiagnostic process in university mental health, yet the mechanisms linking dispositional vulnerabilities to psychological distress and positive wellbeing remain insufficiently understood. This study examined whether perceived stress mediates the associations of psychologica...
M. Paladines-Costa, V. López-Guerra, E. Sarriá et al.· Frontiers in Public Health· 0 citations
Abstract Background Young child depressive symptoms are associated with various concurrent and future psychiatric problems, indicating early transdiagnostic risk for psychopathology. We now need studies that identify and test the robustness, reliability, and validity of early emerging depressive symptom dimensions, exa...
Nicolas L. Camacho, Kirsten E. Gilbert, R. Tillman et al.· JCPP Advances· 0 citations
OBJECTIVES
To investigate whether alexithymia is uniquely associated with major dimensions of psychopathology beyond maladaptive personality trait dimensions.
METHOD
We conducted a cross-sectional study using archival data collected from a diagnostically heterogeneous sample of psychiatric outpatients (N = 154). Pati...
Cheyenne S. McIntyre, Tay-La T. C. Lee, G. J. Taylor et al.· Journal of Psychiatric Resea...· 0 citations
OBJECTIVE
The DSM-5 Alternative Model for Personality Disorders (AMPD) and Kernberg's object relations theory are prominent frameworks for assessing personality dysfunction. This study investigates their structural overlap and evaluates their specific capacity to predict clinical outcomes using a multi-method approach....
T. Kiss, G. Rubovszky, Z. Demetrovics et al.· International journal of psy...· 0 citations
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