Comparative Safety and Efficacy of Dual Antiplatelet Therapy Regimens in Flow Diversion for Intracranial Aneurysms: a Systematic Review and Network Meta-Analysis.
Current FD-specific evidence is insufficient to establish superiority, inferiority, or equivalence among clopidogrel-, ticagrelor- and prasugrel-based DAPT regimens across ischemic, hemorrhagic, functional, and survival outcomes.
Shorter DAPT durations (1 & 3 months) were associated with reduced bleeding without evidence of increased ischemic risk compared with the conventional 12-month strategy, suggesting it may represent a pragmatic threshold for DAPT abbreviation.
Admire Hlupeni, Mehran Jalilzadehbinazar, R. J. Liceralde et al.· PLoS ONE· 0 citations
Ischemic stroke remains a major contributor to global mortality and long-term disability, with antiplatelet therapy representing a fundamental strategy for secondary prevention. Cilostazol and clopidogrel are widely utilized antiplatelet agents; however, existing comparative evidence on their safety and efficacy, parti...
Kadek Kovaleviska Okaniawan, N. Maheswari, Putu Enrico Pramana Okaniawan et al.· Jurnal kedokteran dan keseha...· 0 citations
Introduction: Stent-assisted coil embolisation and flow diversion have expanded the endovascular armamentarium for acutely ruptured wide-necked and complex intracranial aneurysms, but these devices oblige dual antiplatelet therapy in patients who have just sustained subarachnoid haemorrhage and frequently require emerg...
Anissa Putri Almira, Yoyok Subagio· International journal of med...· 0 citations
Abstract Background Catheter-directed thrombolysis (CDT) has emerged as a reperfusion strategy for intermediate-risk and high-risk pulmonary embolism (PE), potentially improving thrombus resolution while reducing bleeding risk compared with systemic thrombolysis. However, evidence comparing CDT with anticoagulation alo...
A. Simanjuntak, F. Wijayanto, C. D. Tristan et al.· Open Heart· 0 citations
BACKGROUND AND OBJECTIVES
Dual antiplatelet therapy (DAPT) is an essential component of medical management after flow diversion. To our knowledge, no studies have compared DAPT regimens using ticagrelor vs clopidogrel in patients undergoing flow diversion with newer generation surface-modified stents. Our study compare...
Joanna M. Roy, B. Musmar, M. Pontarelli et al.· Neurosurgery· 0 citations
BACKGROUND AND OBJECTIVES
The optimal antithrombotic therapy after carotid artery stenting (CAS) in patients requiring oral anticoagulation is uncertain; in particular, the safety and effectiveness of combining direct oral anticoagulants (DOACs) with single antiplatelet therapy (SAPT) compared with DOACs combined with...
P. Pekyi-Boateng, C. Sollenberger, Georgios S. Sioutas et al.· Neurosurgery· 1 citation
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