Diabetes Treatment Regimen as a Determinant of Lipid Goal Attainment in Patients with Type 2 Diabetes Mellitus Receiving Atorvastatin Therapy

Effects of statins on glycemic control and cardiovascular events in patients with new-onset type 2 diabetes: a retrospective cohort study

In patients with new-onset T2D, early statin initiation is associated with worse short-term glycemic improvement and a greater need for escalating glucose-lowering therapy; however, it is also associated with a substantial reduction in the long-term MACE risk.

[Expert consensus on initial combination lipid-lowering therapy in patients with type 2 diabetes mellitus and hypertension (2026)].

Treatment Gap in Very High-Risk Patients with Cardiorenal Disease: An Analysis of the Implementation of Evidence-Based Therapies

Background: In patients with type 2 diabetes mellitus (T2DM) and cardiorenal disease, various therapies reduce cardiovascular and renal events. However, their implementation in clinical practice remains suboptimal. Objective: To quantify the treatment gap in patients with T2DM and very high-risk cardiorenal disease usi...

GUIDELINE-DIRECTED LIPID GOAL ATTAINMENT IN PATIENTS WITH DIABETES AT HIGH AND VERY HIGH CARDIOVASCULAR RISK: REAL-WORLD EVIDENCE OF A PROFOUND TREATMENT GAP

Objective: To evaluate lipid-lowering therapy patterns and the attainment of guideline-directed low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) goals among high and very high-risk patients with diabetes mellitus in a real-world clinical setting.Material and Methods:...

The Complex Interplay Between Dyslipidemic Subjects Living with Type 2 Diabetes and Metabolic Syndrome and Statin Treatment: A Reflection on Adherence and Persistence in the Real World

High levels of blood cholesterol are a major risk factor for atherosclerotic cardiovascular disease and require early and consistent utilization of statins as first-line medications to avoid disabling or even deadly consequences. Nevertheless, real-world treatment adherence is significantly lower than that reported in...

METFORMIN-BASED COMBINATION THERAPY DIFFERENTIALLY MODULATES ADIPONECTIN AND LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Objectives: This study aimed to evaluate the effects of different metformin-based combination therapies on circulating adiponectin levels and lipid profile parameters in patients with type 2 diabetes mellitus (T2DM) and to compare the metabolic responses associated with each therapeutic regimen. Methods: A prospective...