Aug 2026· American Journal of Tropical Medicine and Hygiene· Vol 115, pp. 851-855· 0 citations· 20 references
Medicine
TL;DR
Although limited to a single case and without serological or longitudinal clinical confirmation, these findings underscore the value of unbiased molecular approaches for unresolved febrile illness diagnosis in endemic settings such as the Amazon basin.
Abstract
Orthobunyaviruses, one of the largest and most diverse genera of viruses, include numerous reassortant viruses and present diagnostic challenges due to similar clinical presentations with other arboviral infections. The detection and isolation of a group C orthobunyavirus from a patient with acute febrile illness from Puerto Ospina, Putumayo Department, Colombia during the 2023-2024 Latin American Oropouche fever regional outbreaks are reported in the present study. Using a vertebrate virus-focused metagenomics sequencing approach with VirCapSeq-VERT, a virus related to the Caraparu complex was identified, and a virus isolate was obtained. Although limited to a single case and without serological or longitudinal clinical confirmation, these findings underscore the value of unbiased molecular approaches for unresolved febrile illness diagnosis in endemic settings such as the Amazon basin.
Mpox is a zoonotic disease caused by the monkeypox virus, a double-stranded DNA virus belonging to the genus Orthopoxvirus. The World Health Organization (WHO) declared mpox a Public Health Emergency of International Concern (PHEIC) in July 2022 amid the global clade IIb outbreak and again in August 2024 following an i...
Sílvia Hees de Carvalho, Adriana de Souza Andrade, J. de Moura Freire et al.· Pathogens· 0 citations
Several African countries experienced a surge in acute hemorrhagic conjunctivitis (AHC) cases in 2024. Investigations in Kenya, Mayotte (an Indian Ocean island) and Tanzania identified coxsackievirus A24 variant (CVA24v) as the causative agent. To date, however, limited genomic data exist to elucidate the sources, epid...
J. Morobe, Edidah Ong'era, A. Lambisia et al.· PLoS Pathogens· 0 citations
In South America, the arboviruses that are most noted are those that lead to dengue, Zika, and chikungunya. Nevertheless, there are additional arboviruses that trigger outbreaks, yet do not receive adequate attention, including Oropouche virus (OROV), Mayaro virus (MAYV), Saint Louis Encephalitis virus, Madariaga virus...
Milagros Saavedra-Samillán, Sharon Díaz Velásquez, Marcos A. Castillo Zuta et al.· Transactions of the Royal So...· 0 citations
The detection of NDV sequences in a febrile paediatric patient in the Colombian–Venezuelan border showed the importance of integrating metagenomic diagnostics and One Health surveillance strategies for the early detection of potential emerging zoonotic viruses.
M. Carrillo-Hernández, Lucy Jaimes, K. Ciuoderis et al.· Open Veterinary Journal· 0 citations
Oropouche virus (OROV) is an arboviral pathogen historically confined to the Amazon basin that has undergone an unprecedented geographic expansion across Latin America and the Caribbean since 2023, driven by a novel reassortant lineage with enhanced replicative fitness. Between January and August 2024, more than 8,000...
Laura Beatriz Fernández Feitó, Mariam Alejandra González González, Andy Alonso Pazos et al.· SAP Primary Care· 0 citations
OBJECTIVES
To characterize the clinical, diagnostic and genomic features of chikungunya virus (CHIKV) infection among patients presenting with an acute dengue-like illness in the inland Central Valley of Chiapas, Mexico, during the 2015 outbreak.
METHODS
We retrospectively tested sera from 80 suspected cases using qR...
A. L. Gonzalez-Perez, Ana Vázquez, F. de Ory et al.· International Journal of Inf...· 0 citations
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