Sep 2026· Sport Sciences for Health· Vol 22· 0 citations· 71 references
TL;DR
Key mechanistic evidence demonstrating how targeted GM interventions and structured exercise regimens may synergistically counteract muscle decline is explored, to support the development of innovative therapeutic approaches combining exercise and GM modulation to improve muscle health, functional independence, and healthy ageing trajectories are explored.
Skeletal muscle constitutes one of the largest tissue compartments in the human body and plays fundamental roles in locomotion, posture maintenance, and metabolic regulation. Muscle homeostasis requires a precise balance between protein synthesis and degradation pathways; disruption of this equilibrium leads to patholo...
Bencia Janet, Rutuparna Jena, B. S. Satish Rao et al.· BioMed Research Internationa...· 0 citations
The coordinated optimization of nutrition, exercise, and circadian health, with attention to regularity and timing, may offer complementary benefits exceeding single-domain interventions.
Sih-Yung Lee, Choon Young Kim· Aging and Disease· 0 citations
Sarcopenia is an age-related skeletal muscle disorder characterized by progressive decline in muscle mass, strength, and physical performance, leading to frailty, disability, falls, and increased mortality. Although its pathogenesis is multifactorial, growing evidence indicates that vitamin B complex deficiency contrib...
Kisang Kwon, Sang-Min Lee, Jenny H. Kwon et al.· Journal of Yeungnam Medical...· 0 citations
Sarcopenia is a progressive skeletal muscle disorder in which clinically relevant muscle failure is expressed primarily as reduced muscle strength, with low muscle quantity or quality used to confirm the diagnosis and impaired physical performance indicating greater severity in the EWGSOP2 (European Working Group on Sa...
E. Główczewska-Siedlecka, M. Szafrańska, Agata Doligalska-Dolina et al.· Journal of Gerontology and G...· 0 citations
ABSTRACT Skeletal muscle aging is a major cause of frailty, metabolic dysfunction, and loss of independence in later life, yet it cannot be explained by muscle mass loss alone. Recent single‐cell, multi‐omics, and translational studies show that aged muscle is shaped by coordinated changes in myofibers, stem and stroma...
Introduction Sarcopenia, defined as the loss of skeletal muscle mass, strength, and functional capacity over time, poses a significant health burden among older adults. A growing body of evidence indicates that the gut microbiota contributes to inflammation and metabolic regulation, mitochondrial function, and anabolic...
De-En Wang, Wei Yang, Xiaoming Qin· Frontiers in Cellular and In...· 0 citations
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