Association between longitudinal trajectories of cognitive functioning and all-cause mortality among middle-aged and older adults in South Korea: Exploring the mediating role of oral health-related quality of life
Aug 2026· GeroScience· Vol 48, pp. 6463 - 6474· 0 citations· 38 references
Medicine
TL;DR
While modest, a moderating role of poor OHRQoL on the association between decreasing or low-stable cognitive function trajectories and all-cause mortality was observed, and these findings should be interpreted with caution and require confirmation in future studies.
This longitudinal mediation analysis revealed that individuals experiencing an increasing trajectory of IADL limitations exhibited a higher risk of all-cause mortality, with depressive symptoms partially accounting for this association.
Experiencing an increasing social frailty trajectory was linked to elevated mortality risk in older adults, and subsequent poor cognitive functioning partially accounted for this association.
Seong-Uk Baek, Jin-ha Yoon· The journals of gerontology....· 0 citations
Social frailty was negatively associated with subsequent OHRQoL among middle-aged and older adults and comprehensive interventions aimed at enhancing social engagement and cognitive function may be essential for the improvement of oral health outcomes.
S. Baek, Jin-ha Yoon· The Journal of the American...· 0 citations
Background Nutritional risk is linked to poorer cognitive function in stroke patients, but whether this association is mediated by other factors remains unclear. The purpose of this study is to examine the relationship between nutritional risk and cognitive function, and to evaluate whether activities of daily living (...
Lei Bin, Fang Han, Wan-Hong Luo et al.· Frontiers in Medicine· 0 citations
The importance of identifying target population characteristics, optimal timing, and high-risk groups to support the early detection of hospitalization and mortality risks based on frailty and cognitive decline trajectories is highlighted.
Abstract Background Metabolic syndrome (MetS) has been associated with cognitive decline, yet the role of socioeconomic status (SES) in modifying this association through inflammatory pathways remains unclear. This study investigated whether SES moderates the mediating effect of C-reactive protein (CRP) in the MetS–cog...
Yi-Fan Liang, Shi-Huan Zhong· Research Square· 0 citations
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