Microbial dehalogenation: A critical review on the detoxification paradox and the steering of metabolic pathways

Bacterial Degradation of Persistent Organic Pollutants: From Molecular Mechanisms to Synthetic Biology.

Persistent organic pollutants (POPs) are among the most recalcitrant environmental contaminants due to their chemical stability, hydrophobicity, toxicity, and capacity for long-range transport, yet mechanistic understanding remains fragmented across molecular, cellular, and systems scales, hindering integrated bioremed...

Dehalogenase Enzyme Structure and Its Role in Degradation of Organochlorine Compounds: A Review

Halogenated compounds, including organochlorines, are extensively used as pesticides across agriculture and various industrial applications. These compounds persist in the environment and are toxic, posing significant challenges for remediation efforts. Detoxification strategies such as physical, chemical, and biodegra...

Microbial consortia for pesticide biodegradation: mechanisms, cross-class pathways, and translational challenges

The use of synthetic pesticides estimated at 4.1 million metric tons annually worldwide, has led to widespread contamination of soils and aquatic environments, with documented risks to ecosystem integrity and human health. Physicochemical remediation methods are costly and often generate secondary pollutants and toxic...

Bio-alchemy: a review of bacterial mechanisms for heavy metal sequestration, transformation, and bioremediation

Multi-omics insights into bacterial and fungal bioremediation of Potentially Toxic Elements (PTEs): a critical overview of their applications

This review examines the major advances of the last decade in the application of genomics, transcriptomics, proteomics, and metabolomics and their integration, to investigate molecular mechanisms of microbial adaptation to PTE contamination, supporting the selection of suitable microorganisms or microbial communities a...

Breaking the Ring: Mechanistic Insights Into the Biodegradation of Methylene Blue by Stenotrophomonas maltophilia

The continuous discharge of methylene blue (MB) and other synthetic dyes from textile industries poses significant environmental and public health challenges due to their persistence, toxicity, and resistance to conventional wastewater treatment methods. Among various microbial candidates, Stenotrophomonas maltoph...