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Conference

Architectures of Learning-Driven Intelligence in Modern Medical Decision Environments

Aug 2026 · 2026 International Conference on Secure Information Systems and Technologies (ICSIST) · pp. 833-840 · 0 citations · 14 references

Abstract

Medical decision environments today are becoming more modern through machine learning models based upon structured clinical data, but most deployments are still model-based and disjointed, avoiding system-level insights. Cross-valuation of static predictive baselines on the considered dataset of demographic characteristics, cardiovascular variables, metabolic, and diagnostic labels provided a ROC-AUC of 0.856. Such systems have been shown to be measurably unstable when conditioned to simulated distribution shift, the performance loss of up to 8.7% was evident and variability in calibration and inconsistency in explanation was observed with similar patient profiles. Moreover, their latency of inference was also limited, making them inappropriate in real-time clinical application. The proposed paper is a learning based architectural structure that tries to function at people’s level as opposed to functioning at the isolated classifier level. The suggested architecture recorded a ROC-AUC of 0.910 which is a consistent relative improvement compared to the baseline. Mean inference latency was eliminated with adaptive orchestration and optimized routing by some 18% when controlled working in batch conditions. In moderate drift conditions, degradation was reduced to 2.4 much better than enhancing robustness. Stability for explanation, in terms of attribution variance consistency, was 14 times better with post-hoc baselines than post-pacifism baselines. These findings indicate that elimination of multimodal learning, adaptive inference and embedded governance mechanisms through the application of architectural design produces objective improvements in discrimination, latency, robustness and interpretability. The results confirm the transition to the use of model-centric AI to architecture-based intelligence systems that are specific to contemporary healthcare ecosystems.

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