Jul 2026· Journal of Advanced Academic Research· Vol 13, pp. 119-126· 0 citations· 7 references
TL;DR
Pain and physical and mental component of quality of life both were negatively correlated and there was significant difference between socio-demographic variables with physical and mental component of quality of life.
Abstract
Background and objectives: Osteoarthritis is an age-related disease characterized clinically by pain, functional impairment, disability that may affect quality of life. This study was conducted to evaluate pain and quality of life among patients with knee osteoarthritis.
Methods: A descriptive cross-sectional study was conducted among 162 patients attending Orthopedic Out Patient department of Kathmandu Medical College by convenience sampling method. Numerical Pain Rating Scale was used to assess pain and SF-36 questionnaire was used to assess quality of life through face-to-face interview method. Data analysis was done by SPSS version 20. Descriptive and inferential statistics including non-parametric tests like Mann Whitney U test, Kruskal-Wallis test were applied. Spearman’s Correlation test was used to find out correlation between pain and quality of life, p significant at <0.05 with 95% confidence interval.
Results: In Numerical Pain Rating Scale index, 55.6% had severe pain. The physical component summary score was 33.52±17.63 and mental component summary score was 48.28±21.64. There was significant difference of age and education level with physical component and mental component. The physical and mental component of quality of life was moderately negatively correlated with pain.
Conclusion: Patients with knee osteoarthritis experienced severe pain and reduced score in physical and mental component of quality of life. There was significant difference between socio-demographic variables with physical and mental component of quality of life. Pain and physical and mental component of quality of life both were negatively correlated.
Background: Knee osteoarthritis (OA) is a common cause of pain, functional limitation, and reduced quality of life. Women engaged in household work may experience knee symptoms during middle adulthood. This study aimed to determine the proportion of self-reported knee pain among women engaged in household work in Sukkur and examine its association with quality of life.
Methods: This cross-sectional study included 384 women aged 35-57 years in Sukkur. Participants were recruited through non-probability convenience sampling from households and the Physical Therapy Outpatient Department of Hidayat Hospital. Quality of life was assessed using a modified SF-36, and pain intensity was assessed using the Visual Analogue Scale (VAS) within a structured questionnaire. Data were collected through face-to-face interviews. No clinical examination or radiographic assessment was documented to confirm knee osteoarthritis.
Results: The mean age of the participants was 45.4 ± 6.5 years. Of 384 participants, 151 (39.3%) reported study-defined knee pain. Pain-intensity data were available for 150 participants, of whom 100 (66.7%) reported mild pain, 35 (23.3%) moderate pain, and 15 (10.0%) severe pain. Participants reporting knee pain had significantly lower quality-of-life scores than those without reported knee pain (25.21 ± 6.75 vs 30.11 ± 7.73). The mean difference was -4.90 (95% CI, -6.41 to -3.39), t(382) = -6.37, p < 0.001, with a standardized mean difference of 0.67. Quality-of-life scores did not differ significantly across reported pain-intensity categories (F(2,146) = 2.55, p = 0.082).
Conclusions: In this convenience sample, 39.3% of participants reported knee pain, and reported knee pain was associated with lower quality-of-life scores. Because the sample was selected using non-probability convenience sampling and included outpatient participants, this proportion should not be interpreted as a population prevalence estimate for all women in Sukkur. In addition, because no clinical or radiographic diagnostic criteria were documented, the findings refer to self-reported knee pain rather than confirmed knee osteoarthritis.
Muskan Feroz Mangi, Karam Wassan, Murk Jamali et al.· First Workshop on Insights f...· 0 citations
Knee osteoarthritis (KOA) is a prevalent chronic condition associated with pain, functional limitation, and reduced quality of life. Psychological distress is common among patients with KOA and may influence symptom perception and functional outcomes; however, its independent association with functional disability remains uncertain when major clinical determinants are considered. To examine the associations between psychological distress, pain intensity, and functional disability in patients with knee osteoarthritis. A cross-sectional analytical study was conducted in adult patients with symptomatic knee osteoarthritis. Psychological distress was assessed using the Hospital Anxiety and Depression Scale (HADS), the Patient Health Questionnaire-9 (PHQ-9), and the Mental Component Summary (MCS) of the SF-36. Pain and functional disability were evaluated using the WOMAC index. WOMAC function scores were reverse-coded such that higher values indicate better functional status. Correlation analyses and two complementary multivariable linear regression models were performed to identify factors associated with functional disability. Model 1 adjusted for age, body mass index, and radiographic severity, while Model 2 additionally included pain intensity as a covariate to examine the extent to which pain accounted for the association between depressive symptoms and functional status. Depressive symptoms assessed by the HADS-D were highly prevalent, with all participants (100%) presenting scores ≥ 8, and were significantly associated with pain intensity and functional status in unadjusted analyses. In multivariable regression (Model 1), depressive symptoms were significantly associated with functional disability after adjustment for age, body mass index, and radiographic severity (β = −1.14; 95% CI [− 1.95; −0.33]; p = 0.006), indicating that higher depressive symptom severity was associated with poorer functional status. However, this association was attenuated and no longer statistically significant after additional adjustment for pain intensity (Model 2; β = −0.42; 95% CI [− 0.91; 0.07]; p = 0.092), whereas pain intensity emerged as the strongest independent determinant of functional status (β = 1.99; 95% CI [1.64; 2.35]; p < 0.001). Knee osteoarthritis is associated with a substantial psychological burden. Depressive symptoms are closely linked to pain and functional status; however, their association with functional limitation was largely attenuated after adjustment for pain intensity, suggesting that pain may play a central role in this relationship. These findings support integrated management strategies focusing on both pain control and psychological assessment.
There is a need for an integrated assessment combining clinical evaluation and radiological findings to guide treatment planning for patients with knee OA, and BMI is a major risk factor for osteoarthritis.
Krishna bahadur Bista, R. Dhakal, Bodh Raj Gautam et al.· A Bi-annual South Asian Jour...· 0 citations
Background and purpose: Early knee Osteoarthritis (EKOA), despite minor changes on X-ray, often presents with considerable pain and limitations of function. Pain is considered the primary factor influencing activity restriction, yet the link between severity of pain and measurable functional performance in EKOA remains underexplored.
Method: This pilot study recruited 15 participants (aged 41–55 years) with radiographically confirmed EKOA (Kellgren–Lawrence grade 1 - 2). The severity of pain was measured using the Numeric Pain Rating Scale (NPRS) and disability using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Objective functional ability was examined using the Timed Up and Go (TUG), 30 second Chair Stand Test (CSTS), and Stair Climb Test (SC). Pearson correlation was used to examine pain-function association.
Result: Pain intensity showed a strong positive correlation with TUG (r = 0.903, p = 0.000) and SC (r = 0.791, p =0 .000), and a strong negative correlation with CSTS repetitions (r = –0.925, p =0 .000), confirming that higher pain intensity is linked with greater functional limitation.
Conclusion: This pilot study shows pain intensity strongly predicts functional decline in EKOA. It highlights reduced strength and mobility, underscoring the need for early pain management with strengthening interventions to preserve function and delay progression.
P. S, P. Roshan, Theertha M U· International Journal For Mu...· 0 citations
Summary Objectives: Knee osteoarthritis (KOA) is a common reason for consultation in rehabilitation settings, responsible for pain and restricted autonomy. This study aimed to determine the association between catastrophising and functional limitation in patients followed for KOA in physical medicine and rehabilitation. Methods: This cross-sectional analytical study was conducted from June to August 2025 at the Department of Physical Medicine and Functional Rehabilitation in Taher Sfar University Hospital, Mahdia, Tunisia. Demographic data, the history of KOA as well as the radiographic stage of Kellgren and Lawrence were collected from patients with KOA. Functional impairment was assessed by the Lequesne knee index and catastrophising was assessed by the Pain Catastrophizing Scale (PCS) questionnaire in its Arabic translated and validated version. Results: A total of 90 patients were included with a mean age of 58.76 ± 9.09 years. Most were women (88.9%) and obesity was present in 44.4% of patients. KOA was bilateral in 73.3% of cases. The mean on 100 of the VAS pain at rest was 29.18 ± 19.69 and at walk 57.14 ± 15.81. The mean Lequesne score in the population was 11.33 ± 3.53 and that of the PCS was 23.91 ± 11.28. Significant factors associated with a high level of catastrophizing were the level of education (P = 0.040), obesity (P = 0.007), the radiological stage (P = 0.048) and the Lequesne index (P = 0.019). The mean Hospital Anxiety and Depression Scale (HADS)-depression score was 7.75 ± 2.84 in the low catastrophising group versus 11.04 ± 2.24 in the high catastrophizing group (P <0.001). The mean HADS-anxiety score was 8.20 ± 3.97 versus 12.32 ± 3.83, respectively (P <0.001). Conclusion: These findings demonstrated an association between catastrophising and functional limitation in KOA. Evaluating pain catastrophisation during the follow-up of these patients, may guide and personalise therapeutic strategies, such as cognitive-behavioural approaches, pain management and rehabilitation according to each patient';s needs.
S. Elarem, I. Haddada, Ameni Ameur et al.· Sultan Qaboos University Med...· 0 citations
Background: Knee osteoarthritis (KOA) is a highly prevalent musculoskeletal disorder and a leading cause of pain and functional disability worldwide. Effective management increasingly emphasizes patient education and self-management strategies to reduce pain and restore mobility and functional independence. Objectives: This study aimed to evaluate the effect of a learning package on pain intensity and activities of daily living (ADL) among patients with knee osteoarthritis. Methods: A quasi-experimental one-group pre–post design was conducted in the orthopedic departments and outpatient clinics of Mansoura University Hospital, Egypt. A purposive sample of 71 adult patients diagnosed with KOA was selected. Data were collected using a structured interview questionnaire and the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire, with a focus on the pain and ADL subscales. Measurements were obtained at baseline, one month, and two months post-intervention. Results: The findings demonstrated a statistically significant improvement in both pain and ADL scores after the implementation of the learning package (p<0.001). Pain scores decreased progressively over time, while functional performance in daily activities improved. Conclusions: The structured learning package was effective in reducing pain and enhancing functional ability among patients with KOA. It is recommended that educational and in-service training programs be regularly implemented to enhance patients' knowledge and self-management practices regarding knee osteoarthritis.
Asmaa Gamal Khairy, Wafaa Ismail Shereif, Amany Mohammed Shebl et al.· The Malaysian Journal of Nur...· 0 citations
