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APOE and amyloid‐tau pathology in cognitively unimpaired older adults

Jul 2026 · Alzheimer's & Dementia · Vol 18 · 0 citations · 27 references
Medicine

Abstract

Apolipoprotein E (APOE) genotype shows well‐established dose‐dependent associations with higher amyloid in cognitively unimpaired (CU) adults. In contrast, associations with tau burden and cognition are less well characterized.

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