Open access
Emergence of Genotype 2.3.1 Multidrug-Resistant Salmonella enterica Serovar Typhi Strain, West Africa, 2021-2025.
Medicine
Abstract
Since 2021, a genotype 2.3.1, ciprofloxacin-resistant, multidrug-resistant (MDR) Salmonella enterica serovar Typhi strain increasingly has been detected in persons returning from West Africa. This strain locally acquired 2 different MDR plasmids over a ≈25-year period, underwent chromosomal integration of the IncHI1 plasmid MDR region, and finally acquired a gyrA mutation.