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A Gradio-Based Machine Learning System for Accurate Calorie Burn Prediction

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TL;DR

An AI-driven calorie burn prediction system that leverages machine learning to provide an accessible, low-cost alternative to conventional methods, with potential applications in personalized fitness analytics and digital health platforms.

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Open access Jul 2026

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Machine Learning-Based Prediction of Six-Minute Walk Distance in Children with Obesity

Highlights What are the main findings? Explainable machine learning model, especially XGBoost, outperformed the conventional linear regression in predicting six-minute walk distance (6MWD), as it can better model complex and non-linear relationships between anthropometric parameters in children with obesity. Age is the main predictor of 6MWD in all models, with sex-specific different patterns of body mass index, height and waist circumference. What are the implications of the main finding? The use of SHAP-based explainable AI with machine learning offers can bypass the limitations of conventional linear models and provide a transparent and accurate approach for the assessment of functional exercise capacity in pediatric obesity. These newly derived ML-informed prediction equations are practical tools for field-based clinical assessment tailored to each subgroup, but external validation in large cohorts is required before routine implementation. Abstract Background: The six-minute walk test (6MWT) assesses functional exercise capacity, but existing reference equations for children with obesity rely on traditional linear regression, potentially overlooking complex, non-linear relationships between anthropometric characteristics and functional exercise capacity. Objective: This study aimed to develop and internally validate machine-learning (ML) prediction models and preliminary prediction equations derived from explainable ML models for six-minute walk distance (6MWD) in Tunisian school-aged children with obesity and to compare their predictive performance with a conventional regression-based approach. Methods: We analyzed data from 236 school-aged children with obesity (104 females, 132 males; 6–12 years). Anthropometric measurements included body mass (BM), height, body mass index (BMI), waist circumference (WC), and hip circumference (HC). Five models were evaluated: linear regression, Ridge, Lasso, Elastic Net, and XGBoost. Performance was assessed using five-fold cross-validation and evaluated by the mean absolute error (MAE) and root mean square error (RMSE). Predictor importance was assessed using SHapley Additive exPlanation (SHAP) and Gini importance. Results: XGBoost achieved the best predictive performance, with the lowest MAE (17.4 ± 2.5 m in females and 19.5 ± 1.9 m in males) and RMSE (25.3 ± 3.1 m in females and 26.4 ± 2.2 m in males). Age was the strongest predictor across all models (SHAP: 54.2–62.0%; Gini importance: 0.52–0.69), followed by height and BMI. Sex-specific analyses indicated that, in females, age and BMI contributed ~80% to the cumulative SHAP analysis; whereas, in males, age, height, and WC were the primary factors. Conclusions: ML, particularly XGBoost, significantly improves 6MWD prediction in school-aged children with obesity compared with traditional linear regression. Explainable ML increases model interpretability by evaluating the relative importance of anthropometric predictors. These obesity-specific prediction models may better capture complex non-linear associations between anthropometrics and functional exercise capacity. These initial population-specific models should be validated in larger independent samples before routine use clinical or field settings.

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Y. X. Qin, M. C. Chen · 0 citations
Open access Jul 2026

How can we best predict energy expenditure in preschoolers? A comparison of machine learning models, METs computation and physical activity classification

Objective. The first objective of this study was to refine previously designed machine learning models that predict energy expenditure (EE) of preschool children by modifying the method used to calculate metabolic equivalents (METs). The secondary objective was to compare estimates of time spent in different physical activity intensities across the newly developed models, previously published METs models, existing METs-based models from the literature, and models calibrated using direct observation. Approach. The model training dataset included 35 Canadian children (aged 3.0–5.99 years) equipped with GT9X accelerometers on their right hip. A portable metabolic unit was used to measure EE during a semi-structured protocol consisting of activities ranging from low- to high-intensity. The resulting models were applied to a sample of Canadian preschool children (n = 118; aged 3.0–5.99 years) to estimate time spent in sedentary (SED), light (LPA), moderate-to-vigorous (MVPA), and total physical activity (TPA). A repeated measures ANOVA was used to compare time estimates across models and according to three different configurations of METs activity thresholds. Main results. Results indicated that the newly developed models from Objective 1 produced significantly different estimates of time spent in SED, LPA, MVPA, and TPA compared to both previously published models and other existing METs-based models, highlighting the impact of different approaches to calculating METs. Significance. Model selection and METs calculation methods markedly influenced activity intensity estimates, underscoring the need for consistent methodology. Classification models yielded the most plausible free-living estimates.

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