Open access
Acupuncture Attenuates Neuroinflammation Following Acute Cerebral Infarction by Downregulating SPP1 to Ameliorate Immunological Niches
Jiang-Peng Cao
Xiaoxi Liu
Ling-Fei Wang
Ying Zhou
Lin Zhang
Xu-Juan Chen
Yue-Xin Lin
Lin-Ling Chen
Yuan-Hao Du
Medicine
Abstract
Neuroinflammation following acute cerebral infarction (ACI) critically contributes to disease pathophysiology, with microglia serving as key initial responders. While acupuncture has demonstrated anti‐inflammatory and microglia‐modulating potential, its molecular mechanisms in reshaping immunological niches remain unclear.