CNTN5 Promotes Invasion and Metastasis in Non‐Small Cell Lung Cancer by Regulating YAP1 Nuclear Translocation

Abstract

Non‐small cell lung cancer (NSCLC) is a leading cause of cancer‐related death worldwide, largely owing to its high metastatic potential. Contactin‐5 (CNTN5), a glycosylphosphatidylinositol‐anchored membrane protein, has been implicated in tumor‐related processes; however, its role in NSCLC progression remains unclear. This study aimed to investigate the clinical relevance, biological function, and underlying mechanism of CNTN5 in NSCLC.