Skip to content
Review

Neuropsychiatric Symptoms in Primary Progressive Aphasia: Phenomenology, Circuits, and Clinical Management

Sep 2026 · Current Neurology and Neuroscience Reports · Vol 26 · 0 citations · 56 references
Medicine

TL;DR

This review synthesizes evidence on the phenomenology, neurobiology, assessment, and treatment of neuropsychiatric symptoms in primary progressive aphasia with emphasis on variant-specific patterns and consequences, and decides whether neuropsychiatric features should be incorporated into revised PPA diagnostic criteria.

View source

Similar papers

Sep 2026

Transdiagnostic symptoms and the masking of neurocognitive impairment across the early stages of psychosis.

Impairments in processing speed and verbal learning are well documented in chronic schizophrenia and first episode psychosis (FEP), but the extent to which these patterns generalize to the clinical high-risk (CHR) stage remains less clear. A central interpretive challenge in CHR samples is the prominence of nonpsychoti...

J. Loshin, A. Culbreth, A. Stein et al. · 0 citations
Open access Sep 2026

Conceptualizing cognition and behaviour across amyotrophic lateral sclerosis and frontotemporal dementia.

Cognitive and behavioral dysfunction in frontotemporal dementia (FTD) evolves along a clinical continuum from a clinically silent stage of disease, through a prodromal period, often referred to as mild cognitive impairment (MCI) and/or mild behavioral impairment (MBI), and into a clinically manifest stage recognized by...

M. Benatar, E. Huey, Chiadikaobi Onyike et al. · 1 citation
Review Sep 2026

Communication Difficulties and Management: The Lived Experience of Individuals With Frontotemporal Lobar Degeneration Spectrum Disorders.

Individuals across the FTLD spectrum experience changes to communication that impact their social engagement and quality of life, and recommendations are provided based on the insights and group-level preferences reported here.

Gabriela F. Meade, B. Reinecker, Carrie F. Milliard et al. · 0 citations
Review Open access Oct 2026

A-72: Distinguishing Neuropsychological Features of Progressive bvFTD and Phenocopy phFTD

Objective: This review examines which clinical, neuropsychological, and neuroanatomical features most reliably distinguish phenocopy behavioral variant frontotemporal dementia (phFTD) from progressive behavioral variant frontotemporal dementia (bvFTD). The focus is on diagnostic differentiation in adults presenting w...

Ashanti Lewis, Julie L. Williams · 0 citations
Review Open access Oct 2026

Cognitive predictors of functioning and treatment response in treatment-resistant psychosis: A transdiagnostic approach.

Findings highlight the complex relationship between cognition, daily functioning, and treatment outcomes in TRP and stresses the importance of a transdiagnostic approach to improve understanding and interventions for TRP.

Ivan Caramanna, Daniah Zumrawi, Jessica Lau et al. · 0 citations
Review Open access Sep 2026

Understanding Neuropsychiatric Fluctuations in Parkinson's Disease: From Mechanisms to Management.

BACKGROUND In patients with fluctuating Parkinson's disease (PD), treatment decisions predominantly focus on motor complications, whereas neuropsychiatric symptoms are often regarded as static. Neuropsychiatric fluctuations (NPF), however, are frequent, can rival or exceed motor symptoms in their impact on quality of l...

M. Sousa, D. Amstutz, E. Natera-Villalba et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.