TL;DR
The findings do not support the use of SII as a diagnostic or screening biomarker for dysglycemia and neither index correlated with OGTT-derived insulin sensitivity or early insulin secretion, limiting their clinical utility for detecting dysglycemia.
In adults with well-controlled T2DM, a more proinflammatory diet is associated with higher systemic inflammation, particularly elevated IL 6 levels, which suggest that dietary inflammatory potential may contribute to residual cardiometabolic risk beyond glycemic control.
A composite score derived from universally available routine laboratory parameters — CORI_Ridge — derived from universally available routine laboratory parameters — integrates this signal into a single graded score with moderate out-of-sample discrimination for Grade III obesity; it does not, however, exceed the discri...
HOMA-IR is a reliable and practical marker for identifying IR in children with obesity and appears to play a more dominant role in predicting hepatic steatosis.
In normal-weight adults, IR appears to exhibit a more pronounced association with generalized systemic inflammation reflected by absolute WBC counts rather than ratio-based indices, which serves as a practical marker for early metabolic risk identification in non-obese individuals.
Obese children with prediabetes and diabetes exhibit significantly higher BMI, waist circumference, fasting insulin levels, and HOMA-IR values than euglycemic obese children.
Introduction: The aim of this study was to compare metabolic parameters, inflammatory markers, indicators of iron metabolism and micronutrient levels among groups of obese individuals categorised according to the Triglyceride-Glucose (TyG) index, and to assess the relationship between the TyG index and these parameters...
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