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Pathophysiology of sarcopenia in chronic pancreatitis: Insights from muscle biopsy and molecular profiling.

N. Lohani Sumaira Qamar Deepika Verma S. Gopi Nidhi Singh D. Gunjan Meher Chanda Sharma U. Kanga S. S. Chauhan Namrata Singh N. Dash S. Pal Imteyaz A. Khan Samagra Agarwal A. Saraya
Sep 2026 · Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 0 citations
Medicine

TL;DR

Sarcopenia is common in patients of chronic pancreatitis, and it is characterized by activation of catabolic signaling, impaired anabolic pathways, mitochondrial dysfunction, and defective autophagy, and these findings are hypothesis-generating and may help identify targets to mitigate muscle loss and improve outcomes.

DOI PubMed Semantic Scholar
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