Serum neurofilament light chain serves as a robust biomarker for axonal damage and functional prognosis in GBS, and integrating sNfL quantification with standard clinical grading scales enhances risk stratification and personalized therapeutic management.
BACKGROUND
Guillain-Barré syndrome (GBS) is an acute immune-mediated peripheral neuropathy for which therapeutic apheresis is an established treatment option. Various treatment modalities, including double filtration plasmapheresis (DFPP), are widely used in clinical practice; however, real-world data on their clinical...
Jing-Wen Li, Ying Chen, Jun Wu et al.· Therapeutic apheresis and di...· 0 citations
Advances in serial nerve conduction studies and electrodiagnostic criteria have improved recognition and classification of atypical presentations, including reversible conduction failure, and Parallel developments in clinical assessment and prognostic tools have strengthened prediction of respiratory compromise and fun...
D. Maini· Evolution of Guillain-Barré...· 0 citations
Guillain-Barre syndrome (GBS) is an immune-mediated acute inflammatory polyradiculoneuropathy, with intravenous immunoglobulin (IVIG) and plasma exchange (PLEX) established as standard first-line treatments. A subset of severe overlapping GBS patients carrying multiple pathogenic anti-ganglioside immunoglobulin G (IgG)...
Yue-Qi Wang, Si-Qi Wang, Hui-Juan Fan et al.· Immunotherapy· 0 citations
INTRODUCTION
Generalized myasthenia gravis (gMG) is an autoimmune disorder often associated with anti-acetylcholine receptor antibodies (AChR-Abs). Identifying short-term predictors or indicators of clinical improvement is crucial for optimizing treatment strategies.
METHODS
This post hoc analysis utilized data from...
Zhi-Jun Li, Q. Ke, Jian-Ying Xi et al.· Neurological Therapeutics· 0 citations
Mepolizumab provided sustained long-term disease control with low glucocorticoid exposure in FIP1L1::PDGFRA-negative HES and EoLDAS offers a pragmatic measure of longitudinal disease control that warrants prospective validation and may inform future treat-to-target strategies.
K. Chevalier, François Barde, S. Faguer et al.· Journal of Allergy and Clini...· 0 citations
Background Multisystem inflammatory syndrome in children (MIS-C) is a postinfectious hyperinflammatory condition that can follow a sudden acute respiratory syndrome coronavirus 2 infection. Although several inflammatory markers are used to guide its clinical management, biomarkers that reflect immunomodulatory therapy...
Amrita Pattanaik, Prasad Varamballi, Srilatha Marate et al.· Clinical and experimental pe...· 0 citations
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