Clinical Profile of Patients with Gallstone Disease at a Tertiary Care Hospital

Abstract

Background: Gallstone disease is a prevalent hepatobiliary condition linked to metabolic and lifestyle-related risk factors, exhibiting varied clinical manifestations and complications that lead to a substantial healthcare burden. The objective of this study was to assess the demographic traits, clinical symptoms, imaging results, laboratory irregularities, and related factors in patients suffering from gallstone disease. Methods: : An observational study based in a tertiary care hospital Dhaka, between May and December 2025, involving 110 adult patients diagnosed with gallstone disease via ultrasound. Demographic features, clinical manifestations, comorbid conditions, laboratory results, imaging observations, treatment methods, and short-term results were gathered through a structured proforma and analyzed with SPSS version 26.0. Ethical consent and informed approval were secured before participation.  Results: In a study of 110 patients, gallstone disease was primarily observed among middle-aged women (67.3%), with obesity and metabolic conditions frequently present. Common clinical findings included RUQ pain (90.0%), tenderness (78.2%), and elevated ALT (40.9%). Ultrasonography revealed multiple gallstones in 63.6% of cases, with laparoscopic cholecystectomy being the main treatment modality (82.7%) and demonstrating favorable short-term outcomes. Stones larger than 20 mm showed a significant correlation with acute cholecystitis (p=0.009), indicating a higher risk of inflammatory complications Conclusion: Gallstone disease typically impacted middle-aged women with metabolic risk factors. RUQ pain was the main symptom, ultrasonography assisted in diagnosis, and laparoscopic cholecystectomy resulted in positive outcomes. Bigger stones were linked to an increased risk of acute cholecystitis. Journal of Paediatric Surgeons of Bangladesh (2026) Vol. 17 (2): 87-92