Meta-analysis

Perioperative Biologic and Targeted DMARDs in Patients with Rheumatic Diseases Undergoing Orthopedic Surgery: A Systematic Review and Meta-Analysis.

Z. Khired Mohamed Abdelrazek Maamon Aljonaid H. Ramadan Amr M Soliman N. Elshewy Mohamed Hashem Youssef Abdou H. Alharthi Yasser A. Elmotaleb Gazar Moataz Eldeeb Mona El Sayed Youssef Nazik Abdallah Ahmed Saad E. S. Mohamed

2026 · Clinica Terapeutica · Vol 177 5, pp. 1242-1256 · 0 citations

Medicine

TL;DR

Perioperative continuation of bDMARDs and tsDMARDs increases infection risk but reduces disease flare, and management should be individualized, considering drug-specific risks, including biomarker suppression and thromboembolism.

DOI PubMed Semantic Scholar

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