The Tryptophan Biosynthesis Gene trpE Contributes to Virulence in Mesophilic Aeromonas salmonicida SRW-OG1

Type VII secretion system promotes Streptococcus agalactiae virulence through magnesium acquisition and capsule maintenance

These findings provide the first evidence that the T7SS influences magnesium homeostasis and is essential for maintaining capsule integrity, both of which contribute critically to pathogenicity.

02005 Pomegranate Peel Extracts Suppress the lasI/lasR and rhlI/rhlR Quorum Sensing Systems, eta Gene Expression, Virulence, and Biofilm Formation in Multidrug-Resistant Pseudomonas aeruginosa

Pathogenicity and virulence of Ralstonia solanacearum species complex: Understanding its virulence mechanisms for proper management

ABSTRACT The soil-borne Gram-negative beta-proteobacterium Ralstonia solanacearum species complex (RSSC) causes bacterial wilt, a devastating plant disease that threatens crop production and food security worldwide. In this review, we first summarize current knowledge of RSSC pathogenicity and virulence, focusing on th...

The CpxR–GlvR regulatory axis of Edwardsiella piscicida: a novel virulence regulatory mechanism integrating glycerol metabolism and oxidative stress adaptation

Edwardsiella piscicida is a devastating bacterial pathogen in aquaculture, and in-depth elucidation of its pathogenic mechanisms is essential for establishing effective control strategies; the identification of novel regulatory factors can deepen our understanding of bacterial pathogenesis. Our previous work identified...

A Biotechnological Platform for Gram-Scale Production of Mureidomycin A

Mureidomycin A is a uridyl peptide antibiotic with potent bioactivity against the Gram-negative pathogen Pseudomonas aeruginosa. Crucial bottlenecks impeding further drug development include low compound production in native producers and heterologous hosts, as well as the formation of numerous derivatives, which fur...

Indole decreases the virulence of enterotoxigenic Escherichia coli