Skip to content
Log in
Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

System CpxRA Negatively Regulates the Locus of Enterocyte Effacement of Enterohemorrhagic Escherichia coli Involving 32 σ and Lon protease RETRACTED: The Two-Component

Tracy L. Raivio Jorge A. Girón M. A. de la Cruz Jason Morgan Miguel A. Ares Jorge A Yañez-Santos J. Riordan
· 0 citations · 81 references

TL;DR

The Galleria mellonella model of infection was used and the effect of the loss of the cpx and lon genes in EHEC’s ability to kill the larvae was found, suggesting that virulence in the G. mellonella model is T3SS independent and that CpxA modulates virulence through a yet unknown EHEC-specific factor.

Semantic Scholar
View source

Similar papers

Open access Sep 2026

Regulation and Characterization of the Cex system of enteric pathogens: a pathway for the lipidation and secretion of noncanoncial bacterial lipoproteins

It is shown that CexD is required for CexE’s localization to the outer leaflet of the outer membrane and that a cexD mutant of C. rodentium is attenuated in a murine model, which further define the Rns virulence regulon, the enzymology of a noncanonical acyltranferase and its contributions to pathogenicity.

Z. Rivas, Kacey M. Talbot, Griffin P. Carter et al. · 0 citations
Aug 2026

Comprehensive Genomic Analysis of the pO157 Plasmid in Enterohemorrhagic Escherichia coli O157:H7 Reveals Non-synonymous Variation in Virulence Factors

Comparative pan-genomic and structural analyses indicate that pO157 maintains a highly conserved genomic organization while preserving limited sequence variability among virulence-associated genes.

L. Y. Smith, P. Farace, J. S. García et al. · 0 citations
Open access Sep 2026

Contrasting regulation of the ecp common pilus operon in Citrobacter rodentium: essential roles of a distal element and IHF even in the absence of H-NS

A regulatory architecture distinct from E. coli ecp is defined; the ecpR ortholog is dispensable under the conditions tested, and the nucleoid-associated proteins IHF and H-NS bind the regulatory region; IHF is strictly required for activation even when H-NS is absent.

María I. Isidro-Coxca, Verónica I. Martínez-Santos, Andrés Escalera-Maurer et al. · 0 citations
Open access Aug 2026

The (p)ppGpp Synthetase RelA Contributes to Virulence, Competition Capability and Antibiotic Resistance of Avian Pathogenic Escherichia coli

It is indicated that relA plays a key role in APEC virulence, antibiotic resistance, and membrane homeostasis, and could provide a theoretical basis for targeting the stringent response as a potential strategy to control avian colibacillosis.

Jiangang Hu, Dossêh Jean Apôtre Afayibo, Chang Liu et al. · 0 citations
Open access Aug 2026

Phage-encoded sRNA counteracts xenogeneic silencing in pathogenic E. coli

A prophage-encoded small RNA, HnrS, is identified that functions as an anti-silencing factor by targeting the H-NS paralogue Hha, thereby modulating Hha–H-NS repression of virulence loci including the LEE type III secretion system.

Pranita Poudyal, Brandon M. Sy, Daniel G. Mediati et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.