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Open access

Efficacy of donepezil in patients with chronic tinnitus

Jan 2026 · Clinics · Vol 81 · 1 citation · 32 references
Medicine

Abstract

Highlights • Donepezil has not been evaluated in patients with tinnitus.• Donepezil may offer a pharmacological option for tinnitus management.• THI responder analysis suggested a trend favoring donepezil.• Treatment benefits appeared greater among amplification users.• Complete tinnitus remission occurred only in the donepezil group.

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