ROTEM assays performed in 16 critically ill patients with a prolonged INR correlated well with platelet count, fibrinogen and factor II levels, as well as with DIC score, and EXTEM CFT, alpha and MCF had high accuracy in discriminating patients with and without DIC.
A 15-minute incubation significantly shortens CK-R/CKH-R and marginally decreases CK-MA, potentially normalizing hyper- or hypocoagulable readings, and strict adherence to the manufacturer's incubation protocol is recommended except in emergencies.
Hong Hong, A. Hasenzahl, Mohamed T. Abdelfattah et al.· American Journal of Clinical...· 0 citations
Background
Thromboelastography (TEG) provides a global assessment of coagulation and fibrinolytic activity. This study aimed to evaluate postoperative coagulation changes in patients undergoing lobectomy for lung malignancy using TEG.
Methods
In this prospective observational study, sixteen patients undergoing lobect...
Gizem Keçeci Özgür, Rza Mammadov, Esranur Akpunar et al.· Turk gogus kalp damar cerrah...· 0 citations
Background/Objectives: Sepsis may cause hemostatic disturbances. Viscoelastic hemostatic assays, such as rotational thromboelastometry (ROTEM), may reveal functional hemostatic changes not captured by conventional tests. The study aimed to analyze ROTEM parameters in sepsis-induced coagulopathy (SIC) and overt dissemin...
Piotr F. Czempik· Journal of Clinical Medicine· 1 citation
Introduction: Coagulopathic bleeding after cardiac surgery with cardiopulmonary bypass is a frequent complication associated with increased transfusion requirements, surgical re-exploration, organ injury, and mortality. Fresh frozen plasma has traditionally been the cornerstone of treatment; however, its use requires l...
Paula A. Henríquez Miranda, Betty G. Valencia-Angarita, María Carvajal Perea et al.· Colombian Journal of Anesthe...· 0 citations
Hemolysis is a common and clinically significant preanalytical interference. It occurs when red blood cells break down and release intracellular contents into the matrix. Hemolysis causes both analytical interference and true concentration changes. Clinical laboratories routinely assess the degree of hemolysis to...
Joe Whaley, A. Gewirtz, Hind Malaeb· Clinical Chemistry· 0 citations
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