Aug 2026· Psychiatry and Clinical Neurosciences· Vol 5· 0 citations· 19 references
Medicine
TL;DR
Catatonia can arise in patients with co‐occurring somatic symptom disorder, FNSD, and dissociative disorder, and in this patient, catatonia showed dose‐dependent re‐emergence during tapering of both lorazepam and quetiapine, with remission on re‐escalation.
Abstract
Abstract Background Catatonia is a psychomotor syndrome historically linked to schizophrenia but now recognized across diverse psychiatric, medical, and psychosocial contexts. Detailed reports of catatonia arising amid pronounced psychosocial vulnerability remain scarce. We describe catatonia in a patient with co‐occurring somatic symptom disorder, functional neurological symptom disorder (FNSD), and dissociative disorder that remitted with pharmacotherapy. Case Presentation A man in his 40's with chronic physical illness and recurrent fears of abandonment by his partner developed functional and dissociative symptoms after his partner's surgery was scheduled and was admitted following the sudden onset of fragmented, childlike speech. No specific neurological or medical cause was identified, and no schizophrenia or mood disorder was present. He developed stupor, mutism, posturing, negativism, mannerisms, and stereotypy, meeting DSM‐5‐TR criteria for catatonia; the Bush–Francis Catatonia Rating Scale (BFCRS) score was 22. Under lorazepam 3 mg/day and quetiapine 600 mg/day, the BFCRS improved to 3 by hospital Day 34, but worsened during dose reduction of either drug and improved on re‐escalation. He was discharged on hospital Day 98 with a BFCRS of 0, with no recurrence at 10 months. Conclusion Catatonia can arise in patients with co‐occurring somatic symptom disorder, FNSD, and dissociative disorder. In this patient, catatonia showed dose‐dependent re‐emergence during tapering of both lorazepam and quetiapine, with remission on re‐escalation. Even when psychosocial factors appear prominent, careful monitoring and gradual dose adjustment may be important for maintaining remission.
Catatonia is a neuropsychiatric syndrome with motor and behavioral symptoms, including mutism, negativism, posturing, stereotypy, and hypoactivity. Although previously linked primarily to psychiatric illness, a variety of medical conditions and substance intoxication or withdrawal have also been implicated. It is impor...
Mary Nance, Miracline Ebijoyeldhas, Mariam Khan et al.· Case Reports in Psychiatry· 0 citations
A severe episode of hyperactive catatonia occurring in a patient with autism spectrum disorder (ASD) and schizophrenia conceptualized as schizoaffective disorder is described, emphasizing the clinical heterogeneity of catatonia and the risk of misattributing catatonic stereotypies to obsessive–compulsive phenomena.
A. Mitrea, D. Lambert, M. Kosel· International Journal of Neu...· 0 citations
Catatonia is often underrecognized and underdiagnosed, particularly in young children. Catatonia occurs secondary to a medical and/or psychiatric etiology. The diagnosis can be supported by validated rating scales, including the Pediatric Catatonia Rating Scale and/or response to a dose of a benzodiazepine, often loraz...
Stephanie A. Lichtor, Mars Robinson, J. Luccarelli et al.· Pediatrics· 0 citations
Background The co-occurrence of seizure-associated psychosis and catatonia in epilepsy is diagnostically challenging, particularly when complex pre-existing psychiatric comorbidities complicate attribution. Few reports describe this triad in the context of an antidepressant switch. Case presentation We report a 44-year...
Maryam Alowais, Zainab Khan, Fares Salamah et al.· Frontiers in Psychiatry· 0 citations
Importance: Catatonia is a neuropsychiatric syndrome characterized by abnormalities in motor behavior, speech, volition, and affect. Although historically associated with schizophrenia, contemporary diagnostic frameworks recognize catatonia as a transdiagnostic condition occurring across psychiatric, medical, and neuro...
Namratha Mohan, A. Sarangi· The Primary Care Companion F...· 0 citations
Autoimmune encephalitis frequently presents with prominent psychiatric symptoms and may mimic primary psychiatric disorders, particularly in the early stages. We report the case of a 38-year-old man who presented with a 2-week history of behavioral disturbance, persecutory ideation, auditory hallucinations, and fluctua...
C. Sequeira, Maria João Brito, J. Andrade et al.· Journal of ECT· 0 citations
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