PLANT-BASED EXPRESSION SYSTEMS IN BIOPHARMACEUTICAL PRODUCTION: A COMPREHENSIVE REVIEW

Abstract

The development of biotechnology has given rise to a paradigm shift in the field of pharmaceutical production, which is the transgenic plant for the synthesis of bioactive substances that play a role in the production of drugs and more. It is known as molecular agriculture, which uses plant genetic technology to produce certain proteins with therapeutic functions, including monoclonal antibodies, hormones, vaccines and other biologically active components. The most important methods are additional methods of minimal cost and potential biosafety. Unlike traditional production systems (cells, bacteria or yeast), plants on a flexible and workable platform, the characteristics of most of the decentralized biological drugs. The techniques of other technologies are glucocerebroside (elements for the treatment of Gaucher disease) in transgenic carrot cells, as well as recombinant treatments against Ebola, HIV and influenza, such as plants such as Nicotiana benthamiana or corn. These results demonstrate the potential in the true nature of plants that they convey in addressing the challenges of the global health situation. However, it is not difficult to undertake, as it is important, it is important to control the products of the biosynthesis, to identify the products of the biosynthesis, to know that it is mandatory for the educational process, the capacity to record the post-protection of the proteins and the factors of the rules and ethics that are related to the GMO in the care of a specialist. The rules and precise rules are also related to the integration of this technology into pharmaceutical systems.