The effect of beta-blockers in heart failure with preserved ejection fraction and atrial fibrillation: systematic review and meta-analysis.

BETA-BLOCKER THERAPY AFTER MYOCARDIAL INFARCTION IN PATIENTS WITHOUT HEART FAILURE: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS

Beta-blocker (BB) therapy after myocardial infarction (MI) in patients with reduced left ventricular ejection fraction (LVEF) is well established. However, recent randomised controlled trials (RCTs) in post-MI patients without significantly impaired LVEF have yielded conflicting results. This meta-analysis aimed...

Impact of beta-blockers on cardiovascular outcomes in myocardial infarction patients with preserved or mildly reduced ejection fraction: Systematic review and meta-analysis of randomized trials.

In this meta-analysis of randomized clinical trials, beta-blocker use was not associated with a significant reduction in the primary composite outcome or in mortality or reinfarction, and should be interpreted with caution in the context of an overall neutral result.

Differential impact of catheter ablation across heart failure phenotypes in atrial fibrillation: a grade assessed systematic review and meta-analysis

Atrial fibrillation (AF) is highly prevalent in heart failure (HF) and is linked to increased mortality and hospitalization in both preserved (HFpEF) and reduced ejection fraction (HFrEF). Catheter ablation (CA) has emerged as an effective rhythm-control strategy beyond medical therapy (MT), but phenotype-specifi...

BETA-BLOCKERS AFTER ACUTE CORONARY SYNDROME: DOES ATRIAL BETA-BLOCKERS AFTER ACUTE CORONARY SYNDROME: DOES ATRIAL FIBRILLATION CHANGE THE EQUATION? FIBRILLATION CHANGE THE EQUATION? A PORTUGUESE MULTICENTRE NATIONAL REGISTRY ANALYSIS A

Anaemia and all-cause mortality in contemporary heart failure with preserved ejection fraction (left ventricular ejection fraction ≥50%): an updated systematic review and meta-analysis

Abstract Aims Anaemia is among the most prevalent comorbidities in heart failure with preserved ejection fraction (HFpEF), but pooled prognostic estimates predate the contemporary left ventricular ejection fraction (LVEF) ≥50% definition and combine legacy with contemporary cohorts. We quantified the association betwee...

Association of Poor Adherence to Guideline-Directed Medical Treatment With Adverse Events Including Fatal Arrhythmia in Heart Failure With Reduced Ejection Fraction: A Nationwide Cohort Analysis.

BACKGROUND AND OBJECTIVES Poor adherence to guideline-directed medical therapy (GDMT) in heart failure with reduced ejection fraction (HFrEF) correlates with increased risks of mortality and hospitalization. Whether it is associated with life-threatening ventricular arrhythmias (VA) remains unclear. We assessed GDMT ad...