TL;DR
It is demonstrated that controlled variation of bio-ionic liquid counter-anions provides a tunable strategy to modulate hydrogel mechanical properties and influence hMSC morphology and viability, offering a versatile platform for the development of next-generation biomimetic scaffolds.
The main aim of this study was to develop a cost‐effective, pH‐sensitive Alginate (Alg), PVA, and chitosan (Cs) (Alg/PVA/Cs) hydrogel biocompatible polymer for controlled drug release of azithromycin. Tetraethyl orthosilicate (TEOS) was used to chemically crosslink the hydrogel, improving its structural integrity and...
Results establish composition-dependent relationships among hydrogel network structure, mechanical resilience, stimulus-responsive transport, and biological performance and support CCE@Cu as a promising responsive dressing for diabetic wound repair, warranting further evaluation of its longer-term safety and efficacy.
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