Effectiveness of platelet-rich fibrin concentrates in alveolar ridge preservation after tooth extraction: A systematic review of randomized clinical trials with tomographic evaluation
Jan 2026· Clinics· Vol 81· 0 citations· 39 references
Medicine
Abstract
Highlights • The sole use of PRF concentrates did not improve alveolar ridge preservation.• Primary studies showed relevant heterogeneity in their methodology and outcomes.• Bias concerns were mainly related to poor blinding and lack of reporting details.
i-PRF appears to be a promising minimally invasive option for managing gingival black triangles; however, larger RCTs with longer follow-up are needed to confirm long-term effectiveness.
Meghana Gangolu, Jaswitha Vintha, R. Boyapati et al.· Journal of the Korean Associ...· 0 citations
Background: Evaluating postoperative healing in free gingival grafts (FGG) stabilized with cyanoacrylate adhesive and prefabricated stents, as alternatives to conventional suturing in the mandibular anterior region, is of clinical significance. These methods may offer comparable outcomes in terms of vascularity and sof...
Ranjith Mari, Anitha Balaji, Madhumitha Aravinth· International Journal of Dru...· 0 citations
Background and Objectives: Platelet-rich fibrin (PRF) has been widely investigated as a biological material to enhance healing after tooth extraction; however, its clinical effectiveness remains uncertain. This systematic review evaluates the available evidence on its effectiveness in post-extraction socket management....
Liene Janaite, Irina Vasiļčenko, I. Čēma et al.· Medicina· 0 citations
This systematic review and network meta-analysis (NMA) aimed to evaluate the effects of platelet-rich fibrin (PRF) in alveolar ridge preservation (ARP), as well as to compare and rank different PRF protocols according to their relative effectiveness.
Electronic searches were conducted in five databases for...
Nayara Teixeira de Araújo Reis, T. Carrera, Roberta de Oliveira Alves et al.· BMC Oral Health· 0 citations
Autologous platelet concentrates (APCs) have been increasingly used to accelerate orthodontic canine retraction; however, their effectiveness and associated clinical outcomes remain unclear. To evaluate the effectiveness of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich...
Xiao-Ya Wang, Yu-Zhen Li, Jia-Wen Shao et al.· Progress in orthodontics· 0 citations
The incorporation of PRF into particulate bone grafts during MSFA enhances histological graft maturation by increasing NFB, without a demonstrable effect on RG, and may be regarded as a low-cost autologous adjunct where accelerated histological graft maturation is the specific objective.
A. A. Derbishi, R. Altayyar, Abdulaziz S Alsubaiei et al.· Surgeries· 0 citations
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