Chemical Profiling and Therapeutic Investigations on Grewia gamblei J.R. Drumm for Potential Antioxidant and Anti-inflammatory Applications: An in vitro and in silico Approach
Aug 2026· Journal of Pharmaceutical Innovation· Vol 22· 0 citations· 98 references
TL;DR
The remarkable antioxidant and anti-inflammatory properties of the methanolic leaf extract, and important pharmacokinetic and molecular interactions of the phytocompounds, support the findings of Grewia gamblei as a natural anti-inflammatory potential.
The current study was carried out to determine the in vitro antioxidant and antidiabetic potential and phytochemical profiling of crude extract obtained from the cone of Magnolia zotictla, and then to integrate it with computational chemistry. Phytochemical profiling was determined via HPLC and GC–MS analysis. In HPLC...
M. Zahoor, U. Shah, Marwa Bibi et al.· Chemistry and Biodiversity· 0 citations
Background: Diabetes mellitus remains a major metabolic disorder for which identification of complementary and novel therapeutic agents is an active area of research. Medicinal plants contain chemically diverse constituents that may modulate carbohydrate-digesting enzymes and other antidiabetic targets.Objective: The p...
Jeyavalli A· Natural Resources for Human...· 0 citations
The phytochemical composition and biological activities of Cistus ladanifer aerial part extracts are evaluated to highlight C. ladanifer as a potent source of bioactive compounds with promising therapeutic applications.
Fatima Zahra Ayyad, M. Lahyaoui, Hajar Lahyaoui et al.· Frontiers in Chemistry· 0 citations
The specific molecular interactions suggest that the bio-functional efficacy of L. canescens might be driven by its phenolic-rich chemical composition and potential multi-target modulation of apoptotic and survival pathways.
Muhammed Gungoren· Scientific Reports· 0 citations
The in vitro and in silico findings could suggest that D. gangeticum extracts had significant antibacterial and antibiofilm activities, and has potential as natural source of lead compounds for developing alternative therapeutic strategies against multidrug-resistant S. aureus.
Background/Objectives: Baccharis dracunculifolia DC. is a medicinal plant and the primary botanical source of Brazilian green propolis. This study aimed to characterize the phytochemical profile of its ethanol extract and evaluate its antioxidant, anti-inflammatory, cytotoxic, and acute oral toxicity profiles. Methods:...
G. R. da Silva, Lucas Pires Guarnier, Arianne Jung Kluck et al.· Pharmaceuticals· 0 citations
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