The Effect of Polycystic Ovarian Syndrome on Development of Diabetes Mellitus by a Multistate Modelling Approach

Abstract

Women with polycystic ovary syndrome (PCOS) are more susceptible to metabolic dysfunction, especially glucose impairment. Previous studies have considered prediabetes (pre‐DM) and diabetes mellitus (DM) as single‐point outcomes without accounting for the transition states. This study aimed to explore the transition between different blood glucose states using a multistate Markov model among women with and without PCOS.