Jul 2026· International Journal of Pharmaceutical Quality Assurance· Vol 16· 0 citations· 18 references
TL;DR
Osteoporotic fractures are prevalent among older adults, particularly in women and those with prior fractures or nutritional deficiencies, and targeted interventions, including nutritional supplementation, physical activity, and fall prevention are essential to reduce fracture risk and improve quality of life.
Abstract
Background: Osteoporotic fractures are a major public health concern among older adults, leading to significant
morbidity, mortality, and reduced quality of life. Identifying prevalence and risk factors is critical for effective
prevention.
Aim: To determine the prevalence of osteoporotic fractures among older adults and evaluate associated risk
factors.
Methodology: A prospective observational study was conducted at the Department of Orthopaedics, Sheikh
Bhikhari Medical College and Hospital, Hazaribagh, Jharkhand, India, from May 2022 to August 2024. Ninety
adults aged ≥60 years with clinically and radiologically confirmed osteoporotic fractures were enrolled.
Demographic, clinical, and lifestyle data were collected, and fracture sites were documented. Bone mineral density
assessment and structured questionnaires captured nutritional and lifestyle risk factors. Statistical analyses
included Chi-square tests and multivariate logistic regression.
Results: Hip fractures were most common (38.9%), followed by vertebral (27.8%) and distal radius (20%)
fractures. Female sex predominated in hip and vertebral fractures (p<0.05). Significant independent risk factors
included age ≥70 years (OR=2.45), female sex (OR=1.78), low calcium intake (OR=2.10), vitamin D deficiency
(OR=1.92), sedentary lifestyle (OR=2.30), and history of previous fractures (OR=3.15). Smoking and alcohol use
were not significantly associated.
Conclusion: Osteoporotic fractures are prevalent among older adults, particularly in women and those with prior
fractures or nutritional deficiencies. Targeted interventions, including nutritional supplementation, physical
activity, and fall prevention, are essential to reduce fracture risk and improve quality of life.
Poor nutritional status was independently associated with high-risk MRI patterns in patients with OVF, and the observed sex differences in acute radiological risk may be partially explained or mediated by differences in baseline nutritional status rather than biological sex itself.
Tatsuya Yasuda, Junichiro Sarukawa, Kaoru Yamazaki et al.· Journal of Orthopaedic Scien...· 0 citations
Risks for vertebral fracture in postmenopausal women include age over 60 years, higher body mass index, history of previous fracture, low lumbar bone density, glucocorticoid use, and rheumatoid arthritis, which significantly increase the risk of vertebral fractures.
Yi He, Jing Zhang· Frontiers in Medicine· 0 citations
A more favorable cumulative lifestyle profile was associated with lower osteoporotic fracture risk across BMD categories in older women, and the potential value of integrated lifestyle assessment as a complementary component of fracture-risk assessment and counseling is supported.
Dojoon Park, H. Koh, Seokwon Jeong et al.· Healthcare· 0 citations
Older adults in long-term care (LTC) facilities are at high risk for fragility fractures due to bone loss, impaired mobility, cognitive decline and polypharmacy. Such fractures increase morbidity, mortality and healthcare costs.
This prospective study evaluated the effectiveness of a multifaceted intervent...
S. Nanda, S. Tripathy, A. Gachhayat et al.· Preventive Medicine· 0 citations
Densitometric osteoporosis was identified in a relevant proportion of women younger than 65 years without traditional risk factors, supporting an individualized approach to bone health assessment.
Josefina Rosmino, M. Pavlove, M. L. Brance et al.· EndoAr· 0 citations
Effective care in cases of male osteoporosis requires an integrated risk-based approach that extends beyond BMD to include clinical risk factors, secondary causes, and functional status, and improved recognition and sex-specific management strategies are essential to reduce the fracture burden and improve long-term out...
Selin Tekin, A. Gürlek· Turkish Journal of Medical S...· 0 citations
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