Open access
Association Between BMI and Tumour Regression After Neoadjuvant Therapy in Oesophageal Cancers: Insights From a German Nationwide Registry
Susanne D. Otto
I. Pozios
Wael Rayya
C. Schineis
S. Malinka
R. Strobel
J. Staudacher
C. Treese
T. Vilz
P. Jaeger
Medicine
Abstract
For locally advanced oesophageal carcinoma, multimodal therapy is the standard of care, but prognosis remains poor. Obesity has risen markedly in the last decades. The impact of obesity on response to neoadjuvant treatment remains unclear. This study evaluates the association between body mass index (BMI) and histopathological tumour regression following neoadjuvant therapy in oesophageal cancer.