Gastroprotective effects of ethanolic leaf extracts of Matricaria chamomilla L. and Albizia lebbeck L. against indomethacin-induced gastric ulcer in Wistar rats: modulation of oxidative stress and inflammatory cytokines

Open access Sep 2026

Protective and therapeutic roles of Phoenix dactylifera L. Zaghloul cultivar leaves extract against ethanol-induced gastric ulcer in rats

The impact of ulcer induction and extract treatment on the expression of the studied genes are demonstrated and support the gastroprotective and therapeutic effects of P. dactylifera leaves extract through antioxidant, anti-inflammatory, and mucosal healing activities.

H. F. Aly, Mohamed I. Mabrouk, Mohamed B. Shalaby et al. · Journal of Molecular Histolo... · 0 citations

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Open access 2026

Gastroprotective and Haematological Effects of Chromolaena Odorata Leaf Extract Against Ethanol-Induced Gastric Injury in Albino Rats

Findings indicate an acute gastroprotective effect of C. odorata pretreatment against ethanol-induced gastric injury; they do not establish therapeutic efficacy in an established ulcer or long-term safety.

Emmanuel C. Agu, A. I. Okafor, Ibeaja Adamma Chinyere et al. · International journal of res... · 0 citations

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Sep 2026

Studying the protective effect of Moringa Oleifera and lansoprazole contra indomethacin –induced gastric ulceration in male rats through prostaglandin modulation and restoration of histological changes

Moringa oleifera is a medicinal plant widely recognized for its rich content of bioactive compounds such as flavonoids, phenolic compounds, alkaloids, tannins, saponins, vitamins, and antioxidants that contribute to its therapeutic potential against various pathological disorders, including gastric ulceration. The pres...

د.حسين محسن كاظم, Walaa Naama · Kerbala Journal of Veterinar... · 0 citations

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Open access Sep 2026

Evaluation of the gastroprotective mechanisms of the ethanol leaves extract of Jatropha multifida in ethanol-induced gastric ulceration in Wistar rats: Integrated in Vivo, biochemical, and in silico study

Jatropha multifida leaf extract confers significant, dose-dependent gastroprotection via antioxidant enhancement, prostaglandin restoration, inflammatory modulation, and COX-2 interaction, supporting its translational phytotherapeutic potential.

Tochukwu R. Eze, I. Orhonigbe, Isioma C. Okonta et al. · Metabolism Open · 0 citations

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Open access Aug 2026

Preliminary gastroprotective effect of aqueous Bixa orellana leaf extract in an HCl/ethanol‑induced gastric ulcer rat model

Aqueous BOE showed a possible dose-related gastroprotective trend, with 150 mg/kg producing the most favorable numerical pattern, but larger dose-response studies with extract standardization, blinded morphometric assessment, ulcer-area and mucus endpoints, and biochemical assays are required before efficacy or mechani...

Asma Syuhaily Mohd Yusof, Y. Yong, L. Fong et al. · Life Sciences, Medicine and... · 0 citations

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Open access Aug 2026

Colocasia esculenta Corm Extract Attenuates Ethanol-Induced Gastric Ulcer by Suppressing NF-κB Expression: An Integrated Network Pharmacology Approach and In Vivo Validation

The corm of Colocasia esculenta (L.) Scott is widely used for food and treating gastric problems. However, its gastroprotective activity remains unexplored. This article aims to investigate the gastroprotective activity of the ethanol extract of C. esculenta corm (EECE) in ethanol-induced gastric ulcer in rats. EECE wa...

Reza Pertiwi, Gofarana Wilar, S. Sumiwi et al. · International Journal of Mol... · 0 citations

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