Quantitative and comparative assessment of Tc-99 m MIBI imaging in parathyroid adenomas: associations with biochemical, morphological, and histopathological.

Assessing the effectiveness of 18F-Fluorocholine PET-CT as the leading imaging technique compared to 99mTc-Sestamibi scans and ultrasonography for diagnosing hyperparathyroidism.

BACKGROUND Accurate preoperative localization of hyperfunctioning parathyroid tissue is paramount for the success of minimally invasive parathyroidectomy in primary hyperparathyroidism (PHPT). Conventional imaging with 99mTc-sestamibi (MIBI) scintigraphy and cervical ultrasonography (US) has significant limitations in...

[Analysis of influencing factors for preoperative negative 99mTc-MIBI imaging in patients with single parathyroid tumor].

THE IMPACT OF SPECT/CT HYBRID IMAGING ON ENHANCING DIAGNOSTIC ACCURACY OF PARATHYROID ADENOMA USING 99MTC-MIBI SCAN IN NUCLEAR MEDICINE DEPARTMENT OF KOSOVO

Aim: The aim of this study was to compare the images obtained from conventional planar gamma camera and hybrid SPECT/CT triple head detectors, both present in our department and to justify the diagnostic accuracy of planar and hybrid images performing the parathyroid scintigraphy. The parathyroid scintigraphy was perfo...

Evaluating the preoperative diagnostic value of 99mTc‐MIBI/99mTcO4 − dual‐isotope SPECT/CT fusion imaging and ultrasonography in suspected primary hyperparathyroidism

Abstract Background Primary hyperparathyroidism (PHPT) is a common endocrine disorder that often requires surgical intervention. Preoperative localization of parathyroid lesions is critical for successful surgery. This study compares the diagnostic value of 99mTc‐MIBI/99mTcO4 − dual‐isotope SPECT/CT fusion imaging and...

Incremental Value of Multimodality Imaging for Preoperative Localization in Primary Hyperparathyroidism: A Stepwise Strategy for Focused Parathyroidectomy

Objective Accurate preoperative localization of the affected parathyroid gland is important for focused parathyroidectomy in primary hyperparathyroidism, yet no single imaging modality is uniformly reliable. This study evaluated the incremental localization benefit of combining ultrasonography (US), 99mTc-sestamibi sci...

Noninvasive differentiation of benign and malignant solid pulmonary nodules using multiparameter dual-layer spectral CT radiomics

A DLCT-based multiparametric radiomics model, integrated with clinical-radiological features, enables accurate preoperative, noninvasive differentiation between benign and malignant SPNs, including subcentimeter nodules.