Sep 2026· Cell Host and Microbe· Vol 34 9, pp.
1698-1703
· 0 citations· 15 references
Medicine
TL;DR
Advances in the development of vaccines, neutralizing antibodies, and small-molecule antiviral therapeutics are discussed.
Abstract
Hantaviruses are zoonotic threats that can cause hemorrhagic fever with renal syndrome and severe cardiopulmonary syndrome. Despite disease severity, there are no approved vaccines or therapeutics available for the prevention or management of hantavirus infections. Here, we discuss advances in the development of vaccines, neutralizing antibodies, and small-molecule antiviral therapeutics.
Despite concerns arising from a recent ship-associated outbreak on the M/V Hondius cruise, current evidence suggests that Andes virus (ANDV) poses a low pandemic risk. Nevertheless, viral evolution, ecological changes, and reservoir host dynamics could drive future emergence of ANDV, underscoring the need for improved...
N. Y. Peng, A. Rojas-Fernandez, J. Deerain et al.· Memórias do Instituto Oswald...· 0 citations
Thirteen cases of hantavirus infection (including three deaths) were detected on a cruise ship returning from Ushuaia. Following discussions, the ship was permitted to dock in the Canary Islands, where passengers were disembarked under safety protocols and sent back to their respective countries for medical monitoring....
P. Bourée, Y. Garedaghi, F. Bisaro et al.· International Journal of Med...· 0 citations
Human cytomegalovirus (HCMV) remains one of the most clinically significant human pathogens, representing a major cause of congenital infection worldwide and a serious threat to immunocompromised individuals, including transplant recipients and HIV/AIDS patients [...].
Alexia Damour, Mathilde Larribau, G. Ligat· Pathogens· 0 citations
The obstacles to demonstrating transmission-blocking efficacy are outlined, from the absence of standardized correlates of protection to the limitations of animal and trial models, and how controlled human infection models, household studies, and field trials could help generate evidence to support regulatory engagemen...
Natural Cryptosporidium infection causes development of protective immunity. Live-attenuated vaccines stimulate both adaptive and "trained" innate immune responses. With advances in parasite genetics, target identification, and in vitro cultivation, we now propose development of a live-attenuated vaccine for cryptospor...
A. C. White, S. M. Dann, Alejandro Castellanos-González· Journal of Infectious Diseas...· 0 citations
Mosquitoes represent a major threat to both human and animal health due to serving as vectors for numerous serious diseases, including malaria, dengue fever, West Nile virus, and encephalitis [...]
Athanasios Giatropoulos· Insects· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
