TL;DR
The Melissa officinalis extract appears to exert inhibitory effects on PTZ-induced seizures in this autism model, with the anticonvulsant effect showed a clear dose-response relationship, indicating dose-dependent efficacy.
: Anxiety disorders are among the most prevalent neuropsychiatric conditions, and conventional anxiolytic drugs are often associated with adverse effects such as sedation, dependence, and tolerance. This has increased the demand for safer herbal alternatives. The present study was designed to evaluate the anxiolytic po...
Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures resulting from abnormal neuronal activity. Limitations of current antiepileptic drugs, including adverse effects and drug resistance, have prompted the search for safer plant-derived alternatives. Allium cepa (onion) peel is a r...
The use of traditional medicine as an alternative to conventional therapeutic drugs for pain management remains highly prevalent in developing countries. This study investigated the antinociceptive effects of a combined ethanol extract of Ananas comosus, Citrus limon, and Zingiber officinale peels (EPLG) in male Wistar...
It is suggested that VPA-treated zebrafish show an increased frequency of aggressive and anxiety-like behaviours, as compared to controls, and acute AO extract treatment was not able to modulate aggressive behaviour in VPA-treated or in healthy zebrafish.
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