Low-molecular-weight Ulva lacinulata extract exhibiting anti-inflammatory and pro-autophagic activities in RAW 264.7 macrophages: a promising candidate for the development of active ingredients targeting low-grade inflammation
The potential of an extract from the green seaweed Ulva lacinulata as a safe and effective functional ingredient for the development of functional food and/or dietary supplements targeting chronic low-grade inflammation is highlighted.
Investigation of the anti-inflammatory potential of AVP-1-2 (DP 27), an inulin-type fructan isolated from A. victorialis, indicated that AVP-1-2 effectively suppressed the mRNA expression and protein secretion of pro-inflammatory cytokines in a cellular model.
Xin-Yang Guo, Xiao-Xiao Xiong, Xue-Qi Wang et al.· Plants· 0 citations
Black goji berry (Lycium ruthenicum Murr.) has been recognized for its immune-regulating and anti-cancer potentials, but its key active components and underlying mechanisms remain unclear. Here, we applied LC–MS/MS to characterize the metabolite profile of L. ruthenicum and performed in vitro assays to evaluate its ant...
Lei Jiang, Ji-Deng Ma, Zhi-Yuan Li et al.· Frontiers in Nutrition· 0 citations
This study highlights WSCE as a potential anti-dermatitis agent, suppressing pro-inflammatory mediators in T+I-stimulated keratinocytes via MAPK and NF-κB regulation and position WSCE as a promising candidate for ISD management.
The ethanolic extract of SMS attenuated LPS-induced inflammatory and oxidative stress responses in RAW 264.7 macrophages, suggesting effects may be associated with the suppression of inflammatory mediator production, reduction in the cellular oxidative stress burden and modulation of proteins involved in cellular stres...
Nianshou Zhao, Hongya Li, Peng Ji et al.· Antioxidants· 0 citations
These findings provide discovery-level molecular insights into the anti-inflammatory effects of JGF in LPS-stimulated macrophages and support further targeted validation of its pharmacological activity as a candidate multi-component anti-inflammatory formula.
S. Yeon, Muhammad A. Alsherbiny, Yu-Ting Sun et al.· Antioxidants· 0 citations
The results from these studies demonstrate that the enriched fraction of Mondia whitei induced vacuolation-associated cytotoxicity through autophagy–lysosome perturbation and caspase-dependent apoptosis, providing mechanistic insight into its anticancer potential.
Saheed O. Anifowose, Mobarak S. Al Mosallam, E. Bahattab et al.· Biomolecules· 0 citations
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