Overall, nanoengineered multiplex biosensors represent a promising route toward accessible blood-based Alzheimer’s disease biomarker profiling, but their implementation in clinical practice will require rigorous analytical validation, scalable manufacturing, and clinically meaningful assay design.
A review examines the potential of nanomaterial-based sensing strategies for developing clinically relevant neurodiagnostics, categorizes them systematically, and links them to biomarker profiles for AD and PD.
Shajahan Azeez, Raj Kumar Chinnadurai, Saravanaraman Ponne et al.· International review of neur...· 0 citations
Neurodegenerative disorders (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and prion diseases, are defined by the gradual deterioration of neurons that frequently occurs prior to the onset of clinically observable symptoms. The early diagnosis of these conditions relies on analytical systems that ar...
Alzheimer’s disease (AD) diagnostic workflows are undergoing a paradigm shift from symptom-centric cognitive assessment to biomarker-guided pathological stratification, fuelling an urgent need for minimally invasive analytical tools to quantify ultralow-concentration pathological markers within peripheral biofluids. Bi...
Jiao Wang, Zi-Jin Wei, Zian Zhao et al.· Biosensing and Biomedicine· 0 citations
The design and engineering of gold-nanomaterial-based colorimetric biosensors for monitoring protein aggregation are presented and the current challenges and emerging opportunities for applying these nanosensors to combat AD are highlighted.
Célia Sahli, Haining Zhu, Kenry· Chemical Communications· 0 citations
Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which early diagnosis remains a major challenge. DNA-based biosensors and aptamer-based biosensors have emerged as complementary platforms for the sensitive and selective detection of Alzheimer's disease biomarkers. DNA biosensors primarily detect...
Y. Pahlavan, Mehran Nozari-Asbemarz, Mojtaba Amani et al.· Talanta: The International J...· 0 citations
Alzheimer's disease (AD) and Parkinson's disease (PD) are considered among the most difficult neurodegenerative diseases because they are progressive, and there are no reliable tools to make early diagnoses. Traditional diagnostic approaches, such as neuroimaging and CSF analysis, are not ideal for rapid clinical scree...
Muhammad Waqas Usmani, Abdur Rahim, Faiza Farid et al.· Talanta: The International J...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
