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Field‐Driven Active Colloids as Distributed Micromachines: Bridging Physics, Control, and Function Across Length Scales

Sep 2026 · Advancement of science · 0 citations · 116 references
Medicine

Abstract

ABSTRACT Field‐driven active colloids offer a route to microscale machines whose behavior can be programmed by external electric and magnetic fields. At the micron scale, thermal fluctuations, hydrodynamic interactions, interparticle forces, and field‐mediated actuation combine to connect active matter physics with control and function. In this Perspective, we frame field‐driven active colloids as distributed micromachines, where power delivery, sensing, control, and function are distributed across particles, applied fields, imaging modalities, and feedback architectures. Electric and magnetic fields enable programmable propulsion, trajectory regulation, collective interactions, and dynamic reconfiguration, but practical deployment remains limited by energy delivery, material compatibility, and feedback constraints in complex environments. We emphasize that progress should be evaluated not only by motion, but by controlling task‐relevant variables that determine successful localization, transport, capture, treatment, release, assembly, and reconfiguration. Closing the loop between sensing, AI/ML, computation, and field‐based actuation will be essential for advancing field‐driven colloids toward adaptive, task‐oriented micromachines.

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