Aug 2026· Neurocritical Care· 0 citations· 31 references
Medicine
TL;DR
Real-world insights into RSE in a resource-limited setting are offered, highlighting preventable causes, management complexity, and high care demands, and favorable outcomes are often achievable.
Favorable functional outcomes are associated with prompt guideline-concordant first-line treatment and shorter seizure duration, and key prognostic determinants of pediatric RSE are consistent across different resource settings.
Beyond the clinical severity of NORSE, the findings show that cohort composition is highly sensitive to the temporal operationalization of consensus criteria, and standardized application of diagnostic timing may therefore be essential for comparability across NORSE studies.
C. Jünemann, Meike Menche, Marc-Philipp Bergmann et al.· Neurological Research and Pr...· 0 citations
A short-term early EEG performed in the first 24 h is associated with refractoriness and its exact role warrants further studies, while DRE and NOSE confer refractoriness.
S. Lodha, Babu Rao Challepalle, Shubho Acharya et al.· Epilepsy & Behavior· 0 citations
Findings highlight the substantial burden of severe neurological complications in children presenting with first-time seizures and underscore the critical role of timely recognition of CSE and CNS infections in resource-limited settings.
Kiều Thị Thúy Huỳnh, V. K. Le, T. Nguyen· Medicine· 0 citations
Treatment timing, rather than drug selection, was the principal determinant of seizure cessation, emphasizing the importance of rapid escalation of therapy in pediatric refractory CSE.
Michael Nabil Halim, Rasha Hussein Aly Hussein, O. El-Rashidy et al.· Epilepsy & Behavior· 0 citations
NCSE did not independently increase mortality, but was associated with greater therapeutic complexity and worse functional outcome at discharge, supporting early EEG monitoring and etiology-guided treatment.
A. Canabal-Berlanga, Isabel Magaña, C. Alvargonzález et al.· Seizure· 1 citation
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