Effects of virtual reality-based aerobic exercise versus traditional aerobic exercise training on physical fitness, functional capacity, and quality of life in individuals with Down syndrome: DOWNFIT (Down Syndrome Fitness Intervention Trial) randomized controlled trial.
Sep 2026· Disability and Rehabilitation· pp.
1-16
· 0 citations· 40 references
Medicine
TL;DR
VR-AE and TAE showed different patterns of short-term improvement in adolescents with DS, highlighting the potential for supervised VR-AE and TAE to serve as practical exercise options that can be tailored to individual rehabilitation goals and preferences.
Abstract
Purpose
To compare the effects of virtual reality-based aerobic exercise (VR-AE) and traditional aerobic exercise (TAE) on on physical fitness, functional capacity, and quality of life (QoL) in adolescents with Down syndrome (DS).
Methods
Forty adolescents with DS (mean age 14.45 ± 1.22 years) were randomized to the VR-AE, TAE, or control group (CG). Both intervention groups completed 20 supervised sessions over 10 weeks. VR-AE involved Xbox Kinect-based exergaming, while TAE consisted of treadmill training. Physical fitness, functional capacity, QoL, physical activity, and enjoyment were assessed at baseline and post-intervention.
Results
Both VR-AE and TAE improved selected anthropometric measures compared with CG (p < 0.05). VR-AE demonstrated greater improvements in flexibility, handgrip strength, and trunk endurance (p < 0.05), whereas TAE produced greater improvements in functional capacity and mobility (p < 0.05). Anthropometric improvements were comparable between intervention groups.
Conclusions
VR-AE and TAE showed different patterns of short-term improvement in adolescents with DS. Whilst these findings should be interpreted cautiously given the relatively small sample size and 10-week intervention period, they highlight the potential for supervised VR-AE and TAE to serve as practical exercise options that can be tailored to individual rehabilitation goals and preferences.
This review will synthesise data from previously published studies and will not involve the collection of primary data, and findings will be disseminated through publication in a peer-reviewed journal and presentation at scientific conferences.
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