Open access
Older adults in more disadvantaged neighborhoods exhibit brain vascular dysfunction
K. W. Law
A. Engstrom
T. Lohman
M. Quiring
A. Kapoor
J. P. Alitin
Danny J. J. Wang
A. Gaubert
K. Rodgers
E. Head
Celina I. Valencia
J. Joyce
F. Ferrer
D. Nation
Medicine
TL;DR
Brain microvascular differences in older adults at rest are examined to find neighborhood deprivation is associated with reduced cerebrovascular reactivity and these findings are independent of Alzheimer’s disease-related pathology.
Abstract
Highlights • This study examines brain microvascular differences in older adults at rest.• Neighborhood deprivation is associated with reduced cerebrovascular reactivity.• Findings are independent of Alzheimer’s disease-related pathology.