TL;DR
Findings support the use of BRAF mutation testing may serve as a complementary tool in the diagnostic assessment of thyroid nodules and suggest its potential role as a complementary diagnostic tool in a Uruguayan population is evaluated.
RAF V600E expression was observed in 35.0% of cases and was predominantly associated with papillary thyroid carcinoma, which supports its diagnostic utility in differentiating papillary thyroid carcinoma from low-risk follicular-patterned lesions.
Genetic alterations play a crucial role in the pathogenesis and progression of papillary thyroid carcinoma (PTC). However, the diagnostic and prognostic significance of specific genetic alterations in PTC remains to be elucidated. This study aimed to evaluate the diagnostic performance of next-generation sequencing...
Background and Objectives: BRAF p.V600E status has diagnostic, prognostic, and therapeutic relevance in colorectal carcinoma. Molecular assays remain the reference methods, whereas mutation-specific BRAF (VE1 clone) immunohistochemistry offers a rapid tissue-based alternative. We evaluated VE1–molecular concordance and...
Objective The goal was to determine the presence of a driver mutation in dogs with and without detectable cancer to set the stage for future cancer prevention research exploiting processes that inhibit cancer development in the presence of such mutations. The objective was to detect the v-raf murine sarcoma viral oncog...
Objective: Colorectal cancer is the leading cause of global mortality. Recently, there has been interest in the molecular targets for treatment of cancer. B-rapidly expanded fibrosarcoma (BRAF) mutations, particularly V600E and nonV600E, are the common mutations with diverse clinical presentations and prognosis. The pr...
Background and Objectives: Bethesda Category IV thyroid nodules present a diagnostic challenge due to their variable risk of malignancy and uncertain cytological features. Therefore, determining the risk of malignancy before surgery is important. This study aims to identify clinical, biochemical, and ultrasonographic f...
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
